C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: bactericidal/permeability-increasing protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101425 BPI 9606 + 20:38260149-38337505 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262865 BPI-002 38304123-38337505 protein_coding
  ENST00000417318 BPI-001 38317649-38337325 protein_coding
  ENST00000418004 BPI-006 38260149-38304332 protein_coding
  ENST00000451435 BPI-008 38260175-38293892 protein_coding
  ENST00000479646 BPI-007 38260206-38288947 processed_transcript
  ENST00000489039 BPI-005 38319786-38321808 processed_transcript
  ENST00000489102 BPI-004 38317672-38335641 processed_transcript
  ENST00000490381 BPI-003 38335473-38337261 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262865ENST00000417318ENST00000418004ENST00000479646ENST00000489102
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262865 6.583±0.00 N/A 0.282±0.00 N/A 0.177±0.00 0.146±0.00 0.017±0.00 0.430±0.00 N/A 5.432±0.00 N/A 0.183±0.06 0.027±0.00 1.158±0.00
ENST00000417318 N/A N/A N/A N/A N/A N/A N/A N/A 0.073±0.00 3.360±0.00 N/A N/A 0.605±0.00 4.916±0.00
ENST00000418004 N/A N/A N/A 0.189±0.00 N/A N/A N/A 0.233±0.00 1.310±0.00 N/A N/A 0.960±0.00 N/A N/A
ENST00000479646 N/A 0.345±0.00 N/A 0.210±0.00 N/A 0.271±0.00 N/A N/A 0.212±0.00 N/A N/A 2.842±0.29 N/A N/A
ENST00000489102 N/A 0.160±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.109±0.00 N/A N/A 2.568±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004NZ CIL_0004NZ_0001 CGP 20:38127387-38260772
CIL_0004O0 CIL_0004O0_0001 CGP 20:38210488-38337505
CIL_00081Y CIL_00081Y_0001 VISTA 20:38219747-38821106
CIL_0004O1 CIL_0004O1_0001 CGP 20:38260149-38377023

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001530 IDA lipopolysaccharide binding
GO:0005737 IEA cytoplasm
GO:0005887 TAS integral component of plasma membrane
GO:0006955 IEA immune response
GO:0008289 IEA lipid binding
GO:0032715 IDA negative regulation of interleukin-6 production
GO:0032717 IDA negative regulation of interleukin-8 production
GO:0032720 IDA negative regulation of tumor necrosis factor production
GO:0042742 IEA defense response to bacterium
GO:0043031 IDA negative regulation of macrophage activation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000052922 Bpi bactericidal permeablility increasing protein protein_coding Mus_musculus

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