C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ring finger protein 125, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101695 RNF125 9606 + 18:32018372-32073213 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000217740 RNF125-001 32018372-32073213 protein_coding
  ENST00000580209 RNF125-002 32037185-32066141 nonsense_mediated_decay
  ENST00000580863 RNF125-005 32042079-32068428 retained_intron
  ENST00000583384 RNF125-003 32041823-32068489 processed_transcript
  ENST00000583814 RNF125-004 32041906-32068550 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000217740ENST00000580209
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000217740 2.548±0.00 1.709±0.00 0.577±0.19 1.297±0.71 1.065±0.02 1.077±0.00 1.082±0.25 1.344±0.51 1.113±0.52 N/A 0.674±0.19 1.052±0.00
ENST00000580209 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.643±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002FN CIL_0002FN_0002 CGP 18:31829173-32073213
CIL_0003X2 CIL_0003X2_0001 CGP 18:32018372-32131561

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0032480 TAS negative regulation of type I interferon production
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000081322 RNF125 ring finger protein 125, E3 ubiquitin protein ligase protein_coding Danio_rerio
ENSMUSG00000033107 Rnf125 ring finger protein 125 protein_coding Mus_musculus

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