C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dihydroorotate dehydrogenase (quinone)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102967 DHODH 9606 + 16:72008588-72027664 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219240 DHODH-201 72008744-72025416 protein_coding
  ENST00000571288 DHODH-004 72008778-72017079 nonsense_mediated_decay
  ENST00000571392 DHODH-001 72015623-72024512 retained_intron
  ENST00000572003 DHODH-006 72014419-72021231 retained_intron
  ENST00000572887 DHODH-002 72008588-72027664 protein_coding
  ENST00000573843 DHODH-005 72014451-72021192 retained_intron
  ENST00000573922 DHODH-008 72012233-72023278 processed_transcript
  ENST00000574309 DHODH-009 72008769-72024238 protein_coding
  ENST00000576145 DHODH-003 72008801-72017106 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000219240ENST00000571392ENST00000572887ENST00000573922ENST00000574309
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000219240 2.036±0.00 3.718±0.00 0.382±0.00 0.596±0.38 1.100±0.73 0.461±0.05 0.418±0.01 2.847±1.41 10.952±10.47 0.515±0.22 3.019±0.00 1.568±0.74 1.512±0.29 2.701±1.16
ENST00000571392 N/A N/A 0.453±0.00 N/A 0.298±0.00 0.648±0.07 0.541±0.00 1.367±0.73 8.406±0.00 0.513±0.13 0.273±0.00 1.075±0.19 0.291±0.00 1.279±0.00
ENST00000572887 0.644±0.00 1.255±0.00 0.134±0.00 N/A N/A 0.286±0.00 N/A 1.457±1.00 3.739±0.00 N/A N/A 0.786±0.19 0.167±0.01 1.441±0.00
ENST00000573922 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.486±0.00 2.526±0.00 N/A
ENST00000574309 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.968±0.00 1.664±0.00 4.895±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098E CIL_00098E_0001 VISTA 16:71920667-72521926
CIL_00098B CIL_00098B_0001 VISTA 16:71941307-72542883

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004152 TAS:IEA dihydroorotate dehydrogenase activity
GO:0005739 IEA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006206 TAS pyrimidine nucleobase metabolic process
GO:0006207 IEA 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006222 IEA UMP biosynthetic process
GO:0007565 IEA female pregnancy
GO:0007595 IEA lactation
GO:0008144 IEA drug binding
GO:0010181 IEA FMN binding
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0031000 IEA response to caffeine
GO:0042493 IEA response to drug
GO:0042594 IEA response to starvation
GO:0043025 IEA neuronal cell body
GO:0043065 IEA positive regulation of apoptotic process
GO:0044205 IEA 'de novo' UMP biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0046134 TAS pyrimidine nucleoside biosynthetic process
GO:0048039 IEA ubiquinone binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0090140 IEA regulation of mitochondrial fission

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000051889 dhodh dihydroorotate dehydrogenase protein_coding Danio_rerio
ENSMUSG00000031730 Dhodh dihydroorotate dehydrogenase protein_coding Mus_musculus

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