C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dihydroorotate dehydrogenase (quinone)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000219240 DHODH-201 ENSG00000102967 9606 + 16:72008744-72025416 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000219240
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000219240 2.036±0.00 3.718±0.00 0.382±0.00 0.596±0.38 1.100±0.73 0.461±0.05 0.418±0.01 2.847±1.41 10.952±10.47 0.515±0.22 3.019±0.00 1.568±0.74 1.512±0.29 2.701±1.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098E CIL_00098E_0001 VISTA 16:71920667-72521926
CIL_00098B CIL_00098B_0001 VISTA 16:71941307-72542883

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004152 TAS:IEA dihydroorotate dehydrogenase activity
GO:0005739 IEA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006206 TAS pyrimidine nucleobase metabolic process
GO:0006207 IEA 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006222 IEA UMP biosynthetic process
GO:0007565 IEA female pregnancy
GO:0007595 IEA lactation
GO:0008144 IEA drug binding
GO:0010181 IEA FMN binding
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0031000 IEA response to caffeine
GO:0042493 IEA response to drug
GO:0042594 IEA response to starvation
GO:0043025 IEA neuronal cell body
GO:0043065 IEA positive regulation of apoptotic process
GO:0044205 IEA 'de novo' UMP biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0046134 TAS pyrimidine nucleoside biosynthetic process
GO:0048039 IEA ubiquinone binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0090140 IEA regulation of mitochondrial fission

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000069058 Dhodh-201 protein_coding Mus_musculus 0 1236
ENSMUST00000123605 Dhodh-001 protein_coding Mus_musculus 0 1236
ENSMUST00000143900 Dhodh-002 protein_coding Mus_musculus 0 865
ENSMUST00000125779 Dhodh-008 retained_intron Mus_musculus 0 739
ENSMUST00000133353 Dhodh-005 nonsense_mediated_decay Mus_musculus 0 739
ENSMUST00000142106 Dhodh-009 retained_intron Mus_musculus 0 640
ENSMUST00000146064 Dhodh-004 retained_intron Mus_musculus 0 608
ENSMUST00000131107 Dhodh-003 retained_intron Mus_musculus 0 508
ENSMUST00000150804 Dhodh-007 nonsense_mediated_decay Mus_musculus 0 466
ENSMUST00000128350 Dhodh-006 protein_coding Mus_musculus 0 455
ENSMUST00000124138 Dhodh-010 retained_intron Mus_musculus 0 235

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