C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: par-6 family cell polarity regulator alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000102981 PARD6A 9606 + 16:67660946-67662778 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219255 PARD6A-001 67660959-67662774 protein_coding
  ENST00000458121 PARD6A-002 67660948-67662778 protein_coding
  ENST00000602551 PARD6A-004 67660946-67662774 protein_coding
  ENST00000602727 PARD6A-003 67661232-67662730 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000219255ENST00000458121ENST00000602551ENST00000602727
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000219255 1.331±0.00 N/A N/A 0.350±0.00 N/A 0.615±0.00 N/A N/A 0.529±0.00 N/A 1.564±0.00 3.540±0.66 1.681±0.12 N/A
ENST00000458121 N/A 2.058±0.00 N/A 7.491±5.01 3.379±0.00 4.097±0.00 1.002±0.00 8.195±0.00 N/A 0.651±0.00 2.769±0.00 3.018±0.19 2.744±0.00 16.437±3.07
ENST00000602551 N/A N/A N/A N/A 0.899±0.00 0.408±0.35 0.166±0.00 0.154±0.00 N/A 1.758±0.00 0.525±0.00 N/A N/A N/A
ENST00000602727 N/A N/A 0.627±0.00 N/A N/A N/A N/A N/A 0.117±0.00 0.392±0.00 N/A 1.250±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00079G CIL_00079G_0001 CGP 16:67657512-67662778
CIL_00078Z CIL_00078Z_0001 CGP 16:67660946-67667265

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005080 IEA protein kinase C binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005923 ISS tight junction
GO:0005938 IEA cell cortex
GO:0007049 IEA cell cycle
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008134 TAS transcription factor binding
GO:0016032 TAS viral process
GO:0017048 ISS Rho GTPase binding
GO:0030742 ISS GTP-dependent protein binding
GO:0034329 TAS cell junction assembly
GO:0042995 IEA cell projection
GO:0043234 IEA protein complex
GO:0045177 IEA apical part of cell
GO:0045216 TAS cell-cell junction organization
GO:0045217 ISS cell-cell junction maintenance
GO:0051301 IEA cell division
GO:0070830 TAS tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069378 pard6a par-6 partitioning defective 6 homolog alpha (C. elegans) protein_coding Danio_rerio
ENSMUSG00000005699 Pard6a par-6 family cell polarity regulator alpha protein_coding Mus_musculus

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