C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103056 SMPD3 9606 - 16:68358325-68448688 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219334 SMPD3-001 68358325-68448688 protein_coding
  ENST00000561749 SMPD3-012 68371901-68448492 protein_coding
  ENST00000563226 SMPD3-002 68361134-68372258 protein_coding
  ENST00000563396 SMPD3-011 68361299-68363693 retained_intron
  ENST00000563455 SMPD3-008 68367452-68371009 processed_transcript
  ENST00000566009 SMPD3-010 68364414-68371031 processed_transcript
  ENST00000566466 SMPD3-007 68368855-68371080 processed_transcript
  ENST00000566723 SMPD3-006 68370974-68448442 processed_transcript
  ENST00000567223 SMPD3-013 68363742-68371031 retained_intron
  ENST00000567811 SMPD3-009 68364580-68371031 retained_intron
  ENST00000568373 SMPD3-003 68361127-68372258 protein_coding
  ENST00000574662 SMPD3-014 68360538-68371005 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyLungOvaryTestisENST00000219334ENST00000574662
Transcript ID Brain Kidney Lung Ovary Testis
ENST00000219334 3.715±1.53 N/A N/A 3.877±0.92 3.669±0.63
ENST00000574662 2.535±0.00 1.368±0.00 1.738±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000CE CIL_0000CE_0001 CGP 16:68284503-68358563
CIL_0000C5 CIL_0000C5_0001 CGP 16:68310974-68448688
CIL_0005WZ CIL_0005WZ_0001 CGP 16:68358325-68576072

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000137 IEA Golgi cis cisterna
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0004767 IEA sphingomyelin phosphodiesterase activity
GO:0005794 IEA Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0006665 TAS sphingolipid metabolic process
GO:0006684 IEA sphingomyelin metabolic process
GO:0006685 TAS sphingomyelin catabolic process
GO:0006687 TAS glycosphingolipid metabolic process
GO:0007049 IEA cell cycle
GO:0030072 IEA peptide hormone secretion
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070608 smpd3 sphingomyelin phosphodiesterase 3, neutral protein_coding Danio_rerio
ENSMUSG00000031906 Smpd3 sphingomyelin phosphodiesterase 3, neutral protein_coding Mus_musculus

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