C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104432 IL7 9606 - 8:78675743-78805523 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263851 IL7-001 78732772-78805523 protein_coding
  ENST00000379113 IL7-201 78732774-78805523 protein_coding
  ENST00000518982 IL7-002 78733048-78805464 nonsense_mediated_decay
  ENST00000519833 IL7-008 78717900-78740082 processed_transcript
  ENST00000520215 IL7-005 78733665-78804928 nonsense_mediated_decay
  ENST00000520269 IL7-004 78733665-78804928 protein_coding
  ENST00000520317 IL7-006 78733665-78805451 nonsense_mediated_decay
  ENST00000521323 IL7-003 78797834-78805120 retained_intron
  ENST00000523959 IL7-007 78675743-78738570 processed_transcript
  ENST00000541183 IL7-202 78732774-78805523 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastKidneyLiverMuscleOvaryTestisENST00000263851ENST00000379113ENST00000520215ENST00000520317
Transcript ID Adrenal Breast Kidney Liver Muscle Ovary Testis
ENST00000263851 2.494±0.00 0.665±0.00 N/A N/A N/A N/A 1.391±0.00
ENST00000379113 N/A N/A 1.115±0.00 N/A 0.201±0.00 0.192±0.00 N/A
ENST00000520215 N/A N/A N/A N/A N/A N/A 4.277±0.00
ENST00000520317 N/A N/A N/A 0.516±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002P2 CIL_0002P2_0001 CGP 8:78516139-78719765
CIL_0002P0 CIL_0002P0_0001 CGP 8:78666047-78805523

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002360 IEA T cell lineage commitment
GO:0005125 IEA cytokine activity
GO:0005126 IEA cytokine receptor binding
GO:0005139 IEA interleukin-7 receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006955 IEA immune response
GO:0006959 TAS humoral immune response
GO:0007267 TAS cell-cell signaling
GO:0008083 ISS:IEA growth factor activity
GO:0008284 TAS positive regulation of cell proliferation
GO:0009887 TAS organ morphogenesis
GO:0010468 IEA regulation of gene expression
GO:0030890 ISS positive regulation of B cell proliferation
GO:0043066 ISS negative regulation of apoptotic process
GO:0043086 IEA negative regulation of catalytic activity
GO:0045453 ISS bone resorption
GO:0045582 ISS positive regulation of T cell differentiation
GO:0046622 IEA positive regulation of organ growth
GO:0048873 IEA homeostasis of number of cells within a tissue
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000040329 Il7 interleukin 7 protein_coding Mus_musculus

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