C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263851 IL7-001 ENSG00000104432 9606 - 8:78732772-78805523 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastTestisENST00000263851
Transcript ID Adrenal Breast Testis
ENST00000263851 2.494±0.00 0.665±0.00 1.391±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002P2 CIL_0002P2_0001 CGP 8:78516139-78719765
CIL_0002P0 CIL_0002P0_0001 CGP 8:78666047-78805523

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002360 IEA T cell lineage commitment
GO:0005125 IEA cytokine activity
GO:0005126 IEA cytokine receptor binding
GO:0005139 IEA interleukin-7 receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006955 IEA immune response
GO:0006959 TAS humoral immune response
GO:0007267 TAS cell-cell signaling
GO:0008083 ISS:IEA growth factor activity
GO:0008284 TAS positive regulation of cell proliferation
GO:0009887 TAS organ morphogenesis
GO:0010468 IEA regulation of gene expression
GO:0030890 ISS positive regulation of B cell proliferation
GO:0043066 ISS negative regulation of apoptotic process
GO:0043086 IEA negative regulation of catalytic activity
GO:0045453 ISS bone resorption
GO:0045582 ISS positive regulation of T cell differentiation
GO:0046622 IEA positive regulation of organ growth
GO:0048873 IEA homeostasis of number of cells within a tissue
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168269 Il7-201 protein_coding Mus_musculus 2e-18 99

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