C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neurofilament, medium polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104722 NEFM 9606 + 8:24913012-24919098 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000221166 NEFM-001 24913012-24919093 protein_coding
  ENST00000433454 NEFM-002 24914942-24919098 protein_coding
  ENST00000437366 NEFM-201 24913764-24919090 protein_coding
  ENST00000518131 NEFM-003 24913761-24918976 protein_coding
  ENST00000521540 NEFM-004 24913764-24918615 processed_transcript
  ENST00000523467 NEFM-006 24913758-24915692 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000221166ENST00000433454ENST00000437366ENST00000518131ENST00000521540ENST00000523467
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000221166 0.021±0.00 2.434±0.00 0.061±0.00 0.047±0.00 N/A N/A N/A N/A N/A 0.697±0.27 0.041±0.00 N/A
ENST00000433454 N/A 60.245±0.00 N/A 0.809±0.00 N/A N/A N/A N/A N/A 0.414±0.00 N/A 2.404±0.00
ENST00000437366 N/A 273.248±0.00 N/A 2.783±0.00 N/A 0.762±0.00 N/A 0.104±0.00 N/A 0.867±0.87 0.011±0.00 6.325±1.12
ENST00000518131 N/A N/A 0.101±0.03 N/A 0.073±0.00 0.385±0.00 0.036±0.01 0.062±0.00 0.045±0.00 0.022±0.00 N/A N/A
ENST00000521540 N/A 5.274±0.00 N/A N/A N/A N/A 0.082±0.00 N/A 0.229±0.00 N/A 0.021±0.00 15.215±0.00
ENST00000523467 N/A 14.049±0.00 0.983±0.00 N/A N/A N/A N/A 0.678±0.00 0.941±0.00 N/A 0.117±0.04 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001YP CIL_0001YP_0002 CGP 8:24913012-24957110

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IEA microtubule cytoskeleton organization
GO:0005198 IEA structural molecule activity
GO:0005200 TAS structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005882 IEA intermediate filament
GO:0005883 IEA neurofilament
GO:0008017 TAS microtubule binding
GO:0008088 IEA axon cargo transport
GO:0030424 TAS axon
GO:0031133 IEA regulation of axon diameter
GO:0031594 IEA neuromuscular junction
GO:0033693 TAS neurofilament bundle assembly
GO:0043005 IEA neuron projection
GO:0045104 IEA intermediate filament cytoskeleton organization
GO:0045110 IEA intermediate filament bundle assembly
GO:0060052 IEA neurofilament cytoskeleton organization
GO:0097418 IDA neurofibrillary tangle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021351 nefma neurofilament, medium polypeptide a protein_coding Danio_rerio
ENSDARG00000043697 nefmb neurofilament, medium polypeptide b protein_coding Danio_rerio
ENSMUSG00000022054 Nefm neurofilament, medium polypeptide protein_coding Mus_musculus

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