C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor suppressor candidate 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104723 TUSC3 9606 + 8:15417215-15766649 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000382020 TUSC3-001 15540223-15766649 protein_coding
  ENST00000503191 TUSC3-011 15417215-15673836 processed_transcript
  ENST00000503731 TUSC3-007 15540283-15764459 protein_coding
  ENST00000506802 TUSC3-004 15540233-15764613 protein_coding
  ENST00000507316 TUSC3-009 15743444-15758277 retained_intron
  ENST00000507400 TUSC3-012 15561619-15673836 processed_transcript
  ENST00000508446 TUSC3-010 15673763-15764418 processed_transcript
  ENST00000509177 TUSC3-013 15623078-15651017 retained_intron
  ENST00000509380 TUSC3-006 15540281-15733645 protein_coding
  ENST00000510836 TUSC3-005 15540279-15764629 nonsense_mediated_decay
  ENST00000511342 TUSC3-014 15743530-15748846 retained_intron
  ENST00000511783 TUSC3-008 15623080-15758277 protein_coding
  ENST00000515859 TUSC3-003 15540227-15764661 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000382020ENST00000503731ENST00000506802ENST00000507316ENST00000507400ENST00000511783ENST00000515859
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000382020 1.219±0.00 0.453±0.00 N/A 2.057±0.62 0.629±0.33 1.256±0.00 1.019±0.22 1.331±0.00 1.074±0.00 1.270±0.03 0.063±0.00 2.365±1.23 4.445±0.00 1.367±0.00
ENST00000503731 10.171±0.00 6.183±0.00 N/A 10.976±0.32 3.324±2.61 6.583±3.47 5.692±4.23 9.273±0.00 1.922±1.18 8.712±5.59 0.517±0.00 10.191±9.85 45.567±7.27 12.320±0.19
ENST00000506802 N/A N/A 1.277±0.00 N/A N/A 1.680±0.00 N/A 4.583±0.00 0.264±0.00 N/A N/A 0.389±0.00 18.019±6.45 4.513±0.00
ENST00000507316 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.084±0.00 N/A N/A N/A
ENST00000507400 6.522±0.00 N/A N/A N/A 3.643±0.22 N/A 2.073±0.00 N/A N/A N/A 1.069±0.00 1.079±0.00 21.133±0.00 N/A
ENST00000511783 3.790±0.00 N/A N/A 7.681±0.00 N/A N/A N/A 1.262±0.00 N/A 3.764±1.70 0.916±0.00 6.985±0.00 N/A N/A
ENST00000515859 3.546±0.00 2.208±0.00 N/A 6.853±2.69 1.143±0.42 5.575±0.00 4.213±0.00 2.505±2.13 N/A 3.865±0.00 N/A 8.547±4.81 23.266±4.29 8.116±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00006V CIL_00006V_0002 CGP 8:14089864-15766649
CIL_000456 CIL_000456_0001 CGP 8:15417215-16567490

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004579 ISS dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005739 ISS mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006487 NAS protein N-linked glycosylation
GO:0008250 IDA oligosaccharyltransferase complex
GO:0015095 IMP magnesium ion transmembrane transporter activity
GO:0015693 IGI magnesium ion transport
GO:0018279 ISS protein N-linked glycosylation via asparagine
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0045454 IEA cell redox homeostasis
GO:0050890 IMP cognition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078854 TUSC3 (1 of 2) tumor suppressor candidate 3 protein_coding Danio_rerio
ENSDARG00000091571 TUSC3 (2 of 2) tumor suppressor candidate 3 protein_coding Danio_rerio
ENSMUSG00000039530 Tusc3 tumor suppressor candidate 3 protein_coding Mus_musculus

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