C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleiotrophin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105894 PTN 9606 - 7:137227341-137343865 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000348225 PTN-001 137227341-137343865 protein_coding
  ENST00000393083 PTN-002 137227364-137343774 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000348225ENST00000393083
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000348225 0.208±0.00 3.807±0.00 2.143±0.00 30.256±8.06 3.744±2.12 9.867±7.81 8.069±5.04 4.271±3.45 2.633±2.13 8.856±5.85 0.508±0.00 4.898±2.92 16.377±6.96 33.558±8.08
ENST00000393083 N/A N/A N/A N/A N/A N/A 0.467±0.00 N/A N/A N/A 0.195±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00023Q CIL_00023Q_0002 CGP 7:136868669-137343865
CIL_0002Q6 CIL_0002Q6_0001 CGP 7:137227341-137847092

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0004864 TAS protein phosphatase inhibitor activity
GO:0005615 TAS extracellular space
GO:0005783 IDA endoplasmic reticulum
GO:0007185 TAS transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0007399 TAS nervous system development
GO:0007612 IEA learning
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0008284 TAS positive regulation of cell proliferation
GO:0030282 IEA bone mineralization
GO:0043086 TAS negative regulation of catalytic activity
GO:0051781 IEA positive regulation of cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045798 ptn pleiotrophin protein_coding Danio_rerio
ENSMUSG00000029838 Ptn pleiotrophin protein_coding Mus_musculus

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