C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 3-hydroxyisobutyrate dehydrogenase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106049 HIBADH 9606 - 7:27525442-27662995 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265395 HIBADH-001 27525442-27662995 protein_coding
  ENST00000425715 HIBADH-005 27531254-27647756 protein_coding
  ENST00000428288 HIBADH-003 27525475-27662868 nonsense_mediated_decay
  ENST00000496814 HIBADH-004 27649224-27662857 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265395ENST00000425715ENST00000428288
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265395 14.394±0.00 6.523±0.00 5.176±0.00 3.835±2.63 14.579±10.17 9.215±5.45 14.398±10.08 14.947±2.87 9.855±7.21 4.394±2.93 9.756±5.91 9.338±8.35 12.409±3.69 9.882±3.49
ENST00000425715 N/A N/A N/A N/A 3.101±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 5.062±0.00
ENST00000428288 8.910±0.00 5.779±0.00 N/A 1.844±0.00 9.010±8.02 8.622±0.00 14.111±0.00 28.596±0.00 15.647±0.00 4.245±0.00 12.619±0.00 9.260±1.91 14.734±6.91 8.366±1.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007OD CIL_0007OD_0002 UCNEbase 7:26506344-27606703
CIL_000811 CIL_000811_0001 VISTA 7:26948649-27549872
CIL_00097P CIL_00097P_0001 VISTA 7:27075631-27678581
CIL_0003P6 CIL_0003P6_0001 CGP 7:27242700-27662995
CIL_0003ZJ CIL_0003ZJ_0001 CGP 7:27525442-27844564

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004616 IEA phosphogluconate dehydrogenase (decarboxylating) activity
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006098 IEA pentose-phosphate shunt
GO:0006574 IEA valine catabolic process
GO:0008442 IDA:IEA 3-hydroxyisobutyrate dehydrogenase activity
GO:0009083 TAS branched-chain amino acid catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007959 hibadhb 3-hydroxyisobutyrate dehydrogenase b protein_coding Danio_rerio
ENSDARG00000036236 hibadha 3-hydroxyisobutyrate dehydrogenase a protein_coding Danio_rerio
ENSMUSG00000029776 Hibadh 3-hydroxyisobutyrate dehydrogenase protein_coding Mus_musculus

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