C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor-type, Z polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106278 PTPRZ1 9606 + 7:121873089-122062036 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000393386 PTPRZ1-001 121873089-122062036 protein_coding
  ENST00000449182 PTPRZ1-002 121873361-122061361 protein_coding
  ENST00000468641 PTPRZ1-007 122033858-122036632 retained_intron
  ENST00000470504 PTPRZ1-008 122034013-122039584 retained_intron
  ENST00000471837 PTPRZ1-003 121873161-121967023 processed_transcript
  ENST00000474500 PTPRZ1-010 122059374-122061692 retained_intron
  ENST00000483028 PTPRZ1-004 122011208-122013312 processed_transcript
  ENST00000483995 PTPRZ1-006 122028434-122032080 retained_intron
  ENST00000489114 PTPRZ1-009 122028218-122034340 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393386ENST00000449182ENST00000470504ENST00000471837ENST00000474500
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393386 N/A 0.014±0.00 0.012±0.00 10.131±3.42 0.043±0.00 1.151±0.00 N/A N/A N/A 0.111±0.00 0.015±0.00 0.097±0.00 0.017±0.00 0.130±0.00
ENST00000449182 0.025±0.00 N/A N/A 6.158±0.00 0.626±0.58 0.568±0.25 0.047±0.03 N/A 0.565±0.00 0.753±0.03 0.060±0.05 0.242±0.13 0.041±0.02 0.193±0.00
ENST00000470504 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.143±0.00 N/A
ENST00000471837 N/A N/A N/A N/A N/A N/A N/A 0.693±0.00 2.033±0.00 2.199±0.00 N/A 0.956±0.00 N/A N/A
ENST00000474500 N/A 0.055±0.00 N/A N/A N/A N/A N/A N/A 0.012±0.00 N/A N/A N/A 0.117±0.02 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003R1 CIL_0003R1_0001 CGP 7:121348851-122062036
CIL_0003R2 CIL_0003R2_0001 CGP 7:121873089-122144280

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0004725 ISS:IEA protein tyrosine phosphatase activity
GO:0005001 TAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005887 TAS integral component of plasma membrane
GO:0006470 TAS:IEA protein dephosphorylation
GO:0007409 IEA axonogenesis
GO:0007417 TAS central nervous system development
GO:0007611 ISS learning or memory
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0035335 ISS peptidyl-tyrosine dephosphorylation
GO:0048709 ISS oligodendrocyte differentiation
GO:0070445 ISS regulation of oligodendrocyte progenitor proliferation
GO:0072534 IEA perineuronal net

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020871 ptprz1b protein tyrosine phosphatase, receptor-type, Z polypeptide 1b protein_coding Danio_rerio
ENSDARG00000051814 ptprz1a protein tyrosine phosphatase, receptor-type, Z polypeptide 1a protein_coding Danio_rerio
ENSMUSG00000068748 Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 protein_coding Mus_musculus

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