C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane protein 106B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106460 TMEM106B 9606 + 7:12211241-12243367 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000396667 TMEM106B-001 12211300-12243367 protein_coding
  ENST00000396668 TMEM106B-002 12211241-12233089 protein_coding
  ENST00000420833 TMEM106B-003 12211270-12230939 nonsense_mediated_decay
  ENST00000442107 TMEM106B-006 12211323-12214885 protein_coding
  ENST00000444443 TMEM106B-004 12211296-12224274 protein_coding
  ENST00000453686 TMEM106B-005 12211309-12215707 processed_transcript
  ENST00000462754 TMEM106B-008 12230358-12232400 retained_intron
  ENST00000492762 TMEM106B-007 12229748-12231529 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000396667ENST00000396668ENST00000462754
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000396667 N/A 0.332±0.00 N/A N/A N/A N/A N/A N/A 0.421±0.00 N/A N/A 0.345±0.00 N/A N/A
ENST00000396668 3.816±0.00 1.804±0.00 3.324±0.00 7.287±0.00 3.562±0.82 5.273±1.88 3.036±0.00 4.819±0.00 4.390±0.71 4.611±2.24 2.380±0.00 4.164±0.86 3.754±1.24 3.513±1.86
ENST00000462754 N/A N/A N/A N/A N/A N/A 7.288±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00022R CIL_00022R_0001 CGP 7:11370357-12243367
CIL_00022S CIL_00022S_0001 CGP 7:12211241-12403941

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005768 IEA endosome
GO:0006810 IEA transport
GO:0008219 IEA cell death
GO:0016021 IEA integral component of membrane
GO:0032418 IMP lysosome localization
GO:0048813 IMP dendrite morphogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035949 tmem106bb transmembrane protein 106Bb protein_coding Danio_rerio
ENSMUSG00000029571 Tmem106b transmembrane protein 106B protein_coding Mus_musculus

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