C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Sec61 beta subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106803 SEC61B 9606 + 9:99222064-99230615 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000223641 SEC61B-001 99222301-99230615 protein_coding
  ENST00000481573 SEC61B-003 99222315-99223180 processed_transcript
  ENST00000498603 SEC61B-002 99222064-99230615 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000223641ENST00000481573ENST00000498603
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000223641 34.696±0.00 55.546±0.00 4.109±0.00 16.096±7.54 24.696±17.40 27.324±15.45 12.037±10.45 58.386±30.49 92.750±85.70 46.328±41.06 7.490±6.66 79.932±48.04 96.084±28.43 39.562±18.69
ENST00000481573 N/A N/A 0.607±0.00 N/A N/A N/A N/A N/A N/A N/A 0.084±0.00 0.848±0.00 N/A N/A
ENST00000498603 N/A N/A N/A N/A 2.084±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 3.596±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007HH CIL_0007HH_0002 CGP 9:99216426-99230615
CIL_0007HI CIL_0007HI_0002 CGP 9:99222064-99866891

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000060 IMP protein import into nucleus, translocation
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0006412 TAS translation
GO:0006614 TAS SRP-dependent cotranslational protein targeting to membrane
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016021 NAS integral component of membrane
GO:0030433 IDA ER-associated ubiquitin-dependent protein catabolic process
GO:0030970 IMP retrograde protein transport, ER to cytosol
GO:0031205 ISS endoplasmic reticulum Sec complex
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0048408 IPI epidermal growth factor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076568 sec61b Sec61 beta subunit protein_coding Danio_rerio
ENSMUSG00000053317 Sec61b Sec61 beta subunit protein_coding Mus_musculus
ENSMUSG00000092116 Gm10320 predicted pseudogene 10320 protein_coding Mus_musculus

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