C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor necrosis factor (ligand) superfamily, member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106952 TNFSF8 9606 - 9:114893343-114930595 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000223795 TNFSF8-001 114902844-114930417 protein_coding
  ENST00000474301 TNFSF8-002 114893723-114904308 processed_transcript
  ENST00000618336 TNFSF8-201 114893343-114930595 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000223795ENST00000474301ENST00000618336
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000223795 0.519±0.00 2.046±0.00 0.075±0.00 0.165±0.02 0.824±0.50 0.305±0.19 0.268±0.02 0.172±0.13 0.409±0.27 N/A 0.043±0.00 0.439±0.17 1.312±0.14 0.092±0.04
ENST00000474301 N/A 4.466±0.00 N/A N/A N/A N/A N/A N/A 0.101±0.00 N/A N/A N/A N/A N/A
ENST00000618336 0.273±0.00 2.525±0.00 N/A 0.085±0.05 0.292±0.15 N/A 0.045±0.00 0.209±0.10 N/A 0.803±0.00 N/A 0.068±0.03 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004OV CIL_0004OV_0001 CGP 9:114784635-114930595
CIL_0004OU CIL_0004OU_0001 CGP 9:114893343-115118257

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005125 IEA cytokine activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005887 TAS integral component of plasma membrane
GO:0006915 TAS apoptotic process
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0008283 TAS cell proliferation
GO:0016020 IEA membrane
GO:0043374 IEA CD8-positive, alpha-beta T cell differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050830 IEA defense response to Gram-positive bacterium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000028362 Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 protein_coding Mus_musculus

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