C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 4C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107077 KDM4C 9606 + 9:6757641-7175648 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000381306 KDM4C-002 6757656-7170932 protein_coding
  ENST00000381309 KDM4C-001 6757656-7175648 protein_coding
  ENST00000401787 KDM4C-010 6757654-6815149 protein_coding
  ENST00000420847 KDM4C-006 7013788-7169829 protein_coding
  ENST00000428870 KDM4C-013 6925501-7175347 protein_coding
  ENST00000438023 KDM4C-011 6757641-7014337 nonsense_mediated_decay
  ENST00000466673 KDM4C-008 7127907-7169884 processed_transcript
  ENST00000480996 KDM4C-004 6805617-6819079 processed_transcript
  ENST00000489243 KDM4C-003 6758103-6893632 processed_transcript
  ENST00000490806 KDM4C-009 7104268-7170212 processed_transcript
  ENST00000494570 KDM4C-005 6984281-6986866 processed_transcript
  ENST00000495890 KDM4C-007 7049192-7104017 processed_transcript
  ENST00000496464 KDM4C-012 6893123-6948214 processed_transcript
  ENST00000543771 KDM4C-014 6758143-7077263 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381306ENST00000381309ENST00000428870ENST00000438023ENST00000480996ENST00000489243ENST00000543771
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381306 N/A N/A N/A N/A 1.631±0.00 N/A N/A 0.776±0.00 0.834±0.00 1.527±0.00 N/A N/A N/A N/A
ENST00000381309 1.339±0.00 2.699±0.00 N/A 1.327±0.12 2.559±0.95 2.425±0.25 0.908±0.37 2.318±0.82 1.088±0.05 3.073±0.12 0.393±0.00 2.745±1.40 1.666±0.28 2.577±1.24
ENST00000428870 1.006±0.00 2.564±0.00 0.888±0.00 0.950±0.00 1.206±0.00 1.315±0.00 0.968±0.00 2.479±0.00 1.199±0.00 1.102±0.00 1.262±0.20 2.182±0.22 1.431±0.00 1.477±0.00
ENST00000438023 N/A N/A 0.480±0.00 N/A N/A N/A N/A N/A N/A 2.002±0.00 N/A N/A N/A N/A
ENST00000480996 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.228±0.00 N/A
ENST00000489243 N/A N/A N/A 3.575±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000543771 1.249±0.00 1.380±0.00 N/A 0.710±0.00 N/A N/A N/A N/A 1.291±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001D7 CIL_0001D7_0001 CGP 9:6757641-7888380

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0005515 IEA protein binding
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0008270 IEA zinc ion binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0019899 IPI enzyme binding
GO:0032454 IMP histone demethylase activity (H3-K9 specific)
GO:0033169 IMP histone H3-K9 demethylation
GO:0046417 IEA chorismate metabolic process
GO:0050681 IPI androgen receptor binding
GO:0051213 IEA dioxygenase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061504 KDM4C lysine (K)-specific demethylase 4C protein_coding Danio_rerio
ENSMUSG00000028397 Kdm4c lysine (K)-specific demethylase 4C protein_coding Mus_musculus

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