C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: KN motif and ankyrin repeat domains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107104 KANK1 9606 + 9:470291-746106 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354485 KANK1-002 504703-734129 retained_intron
  ENST00000382286 KANK1-004 734748-746104 protein_coding
  ENST00000382289 KANK1-003 732442-746102 protein_coding
  ENST00000382293 KANK1-005 706889-746103 protein_coding
  ENST00000382297 KANK1-007 504716-746105 protein_coding
  ENST00000382303 KANK1-001 470291-746105 protein_coding
  ENST00000467541 KANK1-008 470592-484491 processed_transcript
  ENST00000475690 KANK1-000 471467-476769 processed_transcript
  ENST00000489369 KANK1-006 504702-746103 processed_transcript
  ENST00000619269 KANK1-201 504695-746106 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354485ENST00000382286ENST00000382289ENST00000382293ENST00000382297ENST00000382303ENST00000489369ENST00000619269
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354485 N/A N/A 1.695±0.00 0.836±0.00 0.758±0.00 N/A 1.252±0.00 1.332±0.00 4.252±0.00 1.679±0.00 0.607±0.00 1.036±0.00 N/A N/A
ENST00000382286 N/A N/A N/A N/A N/A N/A N/A 7.130±0.00 5.439±0.00 N/A N/A 4.733±0.00 5.365±0.00 N/A
ENST00000382289 N/A 3.335±0.00 N/A N/A N/A 6.192±0.00 N/A N/A 8.240±0.00 2.589±0.00 N/A 5.585±0.00 N/A 11.019±0.00
ENST00000382293 3.182±0.00 1.252±0.00 1.478±0.00 1.506±0.00 10.613±0.00 2.934±0.00 N/A 3.338±0.00 N/A N/A N/A 2.127±0.53 2.184±0.36 N/A
ENST00000382297 8.043±0.00 3.205±0.00 3.148±0.00 3.048±1.61 14.595±11.76 5.280±0.00 18.790±12.92 7.022±1.13 5.617±1.74 2.784±1.32 5.028±3.02 4.939±2.91 15.349±12.38 7.124±1.24
ENST00000382303 N/A N/A 1.050±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.028±0.00 N/A N/A
ENST00000489369 N/A 0.809±0.00 N/A 0.977±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000619269 N/A N/A N/A 0.469±0.00 N/A N/A N/A N/A N/A N/A 2.013±0.00 3.518±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VS CIL_0000VS_0001 CGP 9:214854-746106
CIL_0006YF CIL_0006YF_0002 CGP 9:470291-969090

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008013 IDA beta-catenin binding
GO:0010977 IDA negative regulation of neuron projection development
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0030336 IMP negative regulation of cell migration
GO:0030837 IDA negative regulation of actin filament polymerization
GO:0032587 IDA ruffle membrane
GO:0035024 IMP negative regulation of Rho protein signal transduction
GO:0035413 IMP positive regulation of catenin import into nucleus
GO:0046627 IMP negative regulation of insulin receptor signaling pathway
GO:0090303 IMP positive regulation of wound healing
GO:1900025 IDA negative regulation of substrate adhesion-dependent cell spreading
GO:1900028 IDA negative regulation of ruffle assembly
GO:2000114 IMP regulation of establishment of cell polarity
GO:2000393 IDA negative regulation of lamellipodium morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060102 kank1 KN motif and ankyrin repeat domains 1 protein_coding Danio_rerio
ENSMUSG00000032702 Kank1 KN motif and ankyrin repeat domains 1 protein_coding Mus_musculus

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