C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: KN motif and ankyrin repeat domains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032702 Kank1 10090 + 19:25236975-25434496 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049400 Kank1-001 25236975-25434496 protein_coding
  ENSMUST00000137260 Kank1-003 25395303-25409772 processed_transcript
  ENSMUST00000146647 Kank1-002 25406699-25425984 protein_coding
  ENSMUST00000155788 Kank1-004 25422239-25424508 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049400ENSMUST00000137260ENSMUST00000146647
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049400 4.317±2.63 1.964±0.55 31.059±1.32 1.218±0.69 3.186±1.51 8.070±0.79 6.015±2.47 11.967±2.19 4.334±1.94 6.685±2.86 0.471±0.05 8.467±2.69 8.652±2.71 1.751±0.82
ENSMUST00000137260 N/A 5.154±0.00 N/A N/A 7.157±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000146647 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.968±0.00 N/A 3.140±0.00 2.471±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AF CIL_0009AF_0002 VISTA 19:24645396-25246544
CIL_0000VS CIL_0000VS_0002 CGP 19:24999529-25434496
CIL_0006YF CIL_0006YF_0003 CGP 19:25236975-25604329

Gene Ontology
GO IDEvidence TypeGO Description
GO:0008013 IEA beta-catenin binding
GO:0010977 IEA negative regulation of neuron projection development
GO:0030177 IEA positive regulation of Wnt signaling pathway
GO:0030336 IEA negative regulation of cell migration
GO:0030837 ISO negative regulation of actin filament polymerization
GO:0032587 IEA ruffle membrane
GO:0035024 IEA negative regulation of Rho protein signal transduction
GO:0035413 IEA positive regulation of catenin import into nucleus
GO:0046627 IEA negative regulation of insulin receptor signaling pathway
GO:0090303 IEA positive regulation of wound healing
GO:1900025 IEA negative regulation of substrate adhesion-dependent cell spreading
GO:1900028 IEA negative regulation of ruffle assembly
GO:2000114 IEA regulation of establishment of cell polarity
GO:2000393 IEA negative regulation of lamellipodium morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060102 kank1 KN motif and ankyrin repeat domains 1 protein_coding Danio_rerio
ENSG00000107104 KANK1 KN motif and ankyrin repeat domains 1 protein_coding Homo_sapiens

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