C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family A (ABC1), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107331 ABCA2 9606 - 9:137007227-137028922 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265662 ABCA2-201 137007234-137028288 protein_coding
  ENST00000341511 ABCA2-002 137007227-137028190 protein_coding
  ENST00000371605 ABCA2-202 137007234-137028288 protein_coding
  ENST00000398207 ABCA2-015 137021781-137028873 retained_intron
  ENST00000425423 ABCA2-012 137023813-137028807 retained_intron
  ENST00000431584 ABCA2-021 137011477-137012949 retained_intron
  ENST00000437791 ABCA2-006 137009407-137010384 processed_transcript
  ENST00000459850 ABCA2-013 137007377-137028915 retained_intron
  ENST00000463603 ABCA2-008 137009351-137011016 retained_intron
  ENST00000464157 ABCA2-004 137008236-137008788 processed_transcript
  ENST00000464520 ABCA2-023 137007657-137009183 retained_intron
  ENST00000464876 ABCA2-001 137019426-137028178 retained_intron
  ENST00000466707 ABCA2-010 137017562-137018218 retained_intron
  ENST00000467624 ABCA2-011 137018955-137019363 retained_intron
  ENST00000470535 ABCA2-019 137018783-137020805 nonsense_mediated_decay
  ENST00000476211 ABCA2-018 137021667-137028877 retained_intron
  ENST00000479446 ABCA2-009 137007242-137018219 nonsense_mediated_decay
  ENST00000487109 ABCA2-016 137007377-137028915 nonsense_mediated_decay
  ENST00000488535 ABCA2-014 137012325-137018211 nonsense_mediated_decay
  ENST00000490486 ABCA2-022 137007851-137009578 protein_coding
  ENST00000492260 ABCA2-003 137018212-137028171 retained_intron
  ENST00000494046 ABCA2-017 137020183-137028184 retained_intron
  ENST00000614293 ABCA2-203 137007234-137028922 protein_coding
  ENST00000625103 ABCA2-024 137022941-137028878 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265662ENST00000341511ENST00000371605ENST00000431584ENST00000459850ENST00000464520ENST00000479446ENST00000487109ENST00000488535ENST00000494046
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265662 N/A N/A N/A N/A N/A N/A N/A 3.631±0.00 N/A 0.664±0.55 N/A 1.433±0.63 0.404±0.00 N/A
ENST00000341511 2.877±0.00 1.104±0.00 1.205±0.00 36.740±29.99 2.142±0.00 1.534±0.00 N/A N/A 2.388±0.00 0.765±0.00 N/A 4.187±0.88 2.724±0.49 N/A
ENST00000371605 N/A 1.942±0.00 N/A 1.955±0.00 5.589±0.00 2.575±1.34 3.187±2.98 N/A N/A 0.620±0.52 4.291±0.00 1.162±0.00 0.786±0.38 2.595±0.00
ENST00000431584 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.210±0.00 N/A N/A N/A
ENST00000459850 N/A N/A N/A N/A N/A N/A N/A N/A 0.794±0.00 N/A N/A N/A 0.931±0.00 N/A
ENST00000464520 N/A 6.498±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000479446 1.797±0.00 1.675±0.00 N/A 61.668±0.00 3.613±0.00 N/A N/A 3.985±0.00 N/A 0.247±0.00 0.363±0.00 3.697±1.55 1.378±0.40 2.527±0.01
ENST00000487109 N/A N/A N/A 2.298±0.00 N/A N/A N/A 0.556±0.00 N/A N/A N/A 1.289±0.00 N/A N/A
ENST00000488535 N/A N/A 1.586±0.00 N/A 0.589±0.00 0.582±0.00 0.272±0.00 N/A 0.450±0.00 N/A 0.534±0.00 1.031±0.00 N/A N/A
ENST00000494046 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.166±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 NAS nucleotide binding
GO:0005524 IEA ATP binding
GO:0005764 IDA lysosome
GO:0005765 NAS lysosomal membrane
GO:0005768 IDA endosome
GO:0005815 ISS microtubule organizing center
GO:0006200 IEA ATP catabolic process
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006629 NAS lipid metabolic process
GO:0006810 NAS transport
GO:0016020 IDA membrane
GO:0016021 NAS integral component of membrane
GO:0016023 ISS cytoplasmic membrane-bounded vesicle
GO:0016887 IEA ATPase activity
GO:0032383 IMP regulation of intracellular cholesterol transport
GO:0042493 TAS response to drug
GO:0042626 NAS ATPase activity, coupled to transmembrane movement of substances
GO:0042632 IEP cholesterol homeostasis
GO:0043190 NAS ATP-binding cassette (ABC) transporter complex
GO:0048545 IEP response to steroid hormone
GO:0055085 NAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013500 abca2 ATP-binding cassette, sub-family A (ABC1), member 2 protein_coding Danio_rerio
ENSMUSG00000026944 Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 protein_coding Mus_musculus

Loading