C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: exosome component 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107371 EXOSC3 9606 - 9:37766978-37801437 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000327304 EXOSC3-001 37779714-37785057 protein_coding
  ENST00000396521 EXOSC3-002 37780607-37785064 protein_coding
  ENST00000465229 EXOSC3-005 37766978-37785061 nonsense_mediated_decay
  ENST00000465860 EXOSC3-007 37781804-37784745 retained_intron
  ENST00000482614 EXOSC3-008 37780806-37801437 processed_transcript
  ENST00000489414 EXOSC3-009 37780691-37800709 processed_transcript
  ENST00000490516 EXOSC3-004 37780588-37784713 processed_transcript
  ENST00000496910 EXOSC3-006 37783872-37784745 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartLiverLungOvaryPlacentaTestisENST00000327304ENST00000396521ENST00000489414
Transcript ID Heart Liver Lung Ovary Placenta Testis
ENST00000327304 1.945±0.00 6.947±0.00 5.745±0.00 6.932±0.00 N/A N/A
ENST00000396521 N/A N/A N/A 39.867±0.00 29.506±0.00 57.744±0.00
ENST00000489414 N/A N/A N/A 27.614±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006TI CIL_0006TI_0001 CGP 9:37651000-37778972
CIL_00081A CIL_00081A_0001 VISTA 9:37738698-38340102
CIL_0006TH CIL_0006TH_0001 CGP 9:37753803-37801437
CIL_0006TG CIL_0006TG_0001 CGP 9:37766978-37867666

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000175 NAS 3'-5'-exoribonuclease activity
GO:0000176 IDA nuclear exosome (RNase complex)
GO:0000177 IDA cytoplasmic exosome (RNase complex)
GO:0000178 IDA exosome (RNase complex)
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006364 IDA rRNA processing
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0035327 IMP transcriptionally active chromatin
GO:0043928 IMP exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0045006 IDA DNA deamination
GO:0045190 ISS isotype switching
GO:0045830 IEA positive regulation of isotype switching
GO:0071034 IMP CUT catabolic process
GO:0090503 NAS RNA phosphodiester bond hydrolysis, exonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029187 exosc3 exosome component 3 protein_coding Danio_rerio
ENSMUSG00000028322 Exosc3 exosome component 3 protein_coding Mus_musculus

Loading