C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: exosome component 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028322 Exosc3 10090 - 4:45316613-45342732 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030003 Exosc3-001 45316613-45320629 protein_coding
  ENSMUST00000130843 Exosc3-002 45317489-45320604 processed_transcript
  ENSMUST00000143111 Exosc3-003 45316794-45320336 processed_transcript
  ENSMUST00000152056 Exosc3-004 45316954-45342732 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030003ENSMUST00000130843ENSMUST00000143111ENSMUST00000152056
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030003 N/A 28.141±7.50 9.870±0.20 8.696±2.25 10.741±0.75 7.756±2.53 2.450±0.17 6.262±0.97 15.230±9.47 7.155±0.56 5.617±0.47 21.781±11.38 26.674±11.35 21.249±2.04
ENSMUST00000130843 11.963±3.33 32.107±8.38 9.013±0.00 8.665±1.18 10.840±1.43 13.043±3.17 4.836±1.66 8.069±2.48 8.161±3.40 11.018±1.51 N/A 18.335±4.92 7.275±0.00 12.506±0.81
ENSMUST00000143111 N/A N/A N/A 11.061±0.00 N/A N/A N/A N/A N/A N/A N/A 23.966±0.00 41.893±14.66 52.345±0.00
ENSMUST00000152056 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 35.077±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081A CIL_00081A_0002 VISTA 4:45205842-45807105
CIL_0006TH CIL_0006TH_0002 CGP 4:45297127-45342732
CIL_0006TG CIL_0006TG_0002 CGP 4:45316613-45379759

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000176 IEA nuclear exosome (RNase complex)
GO:0000177 IEA cytoplasmic exosome (RNase complex)
GO:0000178 ISS exosome (RNase complex)
GO:0003674 ND molecular_function
GO:0003723 IEA RNA binding
GO:0004527 IEA exonuclease activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005730 ISS nucleolus
GO:0005737 IEA cytoplasm
GO:0006364 IEA rRNA processing
GO:0035327 IEA transcriptionally active chromatin
GO:0043928 IEA exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0045006 IEA DNA deamination
GO:0045190 IMP isotype switching
GO:0045830 IMP positive regulation of isotype switching
GO:0071034 IEA CUT catabolic process
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029187 exosc3 exosome component 3 protein_coding Danio_rerio
ENSG00000107371 EXOSC3 exosome component 3 protein_coding Homo_sapiens

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