C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 3, subunit A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107581 EIF3A 9606 - 10:119033670-119080823 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369144 EIF3A-001 119033670-119080804 protein_coding
  ENST00000462527 EIF3A-002 119056876-119059890 retained_intron
  ENST00000541549 EIF3A-201 119035793-119080823 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000369144ENST00000541549
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000369144 14.844±0.00 16.589±0.00 1.025±0.00 5.287±3.66 10.801±6.69 11.283±7.52 2.393±1.09 3.138±0.96 6.399±3.58 6.809±3.96 18.363±16.61 10.963±4.02 8.771±0.44 10.647±6.15
ENST00000541549 19.376±0.00 N/A N/A 8.747±6.33 11.611±2.98 12.825±3.41 12.474±9.11 9.784±4.75 10.768±0.00 7.684±1.56 52.091±0.00 19.580±6.64 21.367±20.77 20.351±8.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00062M CIL_00062M_0001 CGP 10:118674167-119033732
CIL_0003K9 CIL_0003K9_0001 CGP 10:119029716-119080823
CIL_0005Y7 CIL_0005Y7_0001 CGP 10:119033670-119137984

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001731 IEA formation of translation preinitiation complex
GO:0001732 IDA formation of cytoplasmic translation initiation complex
GO:0003743 IC translation initiation factor activity
GO:0005198 NAS structural molecule activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005852 IDA eukaryotic translation initiation factor 3 complex
GO:0006412 TAS translation
GO:0006413 IC translational initiation
GO:0006446 IEA regulation of translational initiation
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016282 IEA eukaryotic 43S preinitiation complex
GO:0033290 IEA eukaryotic 48S preinitiation complex
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0071541 IEA eukaryotic translation initiation factor 3 complex, eIF3m

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076815 eif3s10 eukaryotic translation initiation factor 3, subunit 10 (theta) protein_coding Danio_rerio
ENSMUSG00000024991 Eif3a eukaryotic translation initiation factor 3, subunit A protein_coding Mus_musculus

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