C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-cell leukemia homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107807 TLX1 9606 + 10:101130505-101137789 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370196 TLX1-001 101130505-101137789 protein_coding
  ENST00000463716 TLX1-002 101131728-101134225 protein_coding
  ENST00000467928 TLX1-003 101131304-101137497 protein_coding
  ENST00000525019 TLX1-005 101134314-101135516 processed_transcript
  ENST00000533319 TLX1-004 101132782-101134215 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverOvaryPlacentaTestisENST00000370196ENST00000467928
Transcript ID Kidney Liver Ovary Placenta Testis
ENST00000370196 0.076±0.00 N/A 1.011±0.45 0.063±0.01 0.127±0.00
ENST00000467928 N/A 0.149±0.00 0.887±0.84 0.044±0.00 0.264±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000940 CIL_000940_0001 VISTA 10:100919065-101519843
CIL_0007ZR CIL_0007ZR_0001 VISTA 10:101034855-101635629
CIL_0001C6 CIL_0001C6_0002 CGP 10:101130505-101229794

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0007417 IEA central nervous system development
GO:0008284 IEA positive regulation of cell proliferation
GO:0030182 IEA neuron differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045165 IEA cell fate commitment
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048536 IEA spleen development
GO:0048645 IEA organ formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003965 tlx1 T-cell leukemia, homeobox 1 protein_coding Danio_rerio
ENSMUSG00000025215 Tlx1 T cell leukemia, homeobox 1 protein_coding Mus_musculus

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