C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T cell leukemia, homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025215 Tlx1 10090 + 19:45150680-45156943 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026236 Tlx1-001 45150680-45156943 protein_coding
  ENSMUST00000174617 Tlx1-002 45151469-45156399 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartLiverMuscleOvaryPlacentaENSMUST00000026236ENSMUST00000174617
Transcript ID Adipose Brain Breast Colon Heart Liver Muscle Ovary Placenta
ENSMUST00000026236 0.012±0.00 0.219±0.00 0.054±0.04 0.017±0.00 0.059±0.04 0.013±0.01 N/A 0.031±0.00 0.008±0.00
ENSMUST00000174617 N/A N/A 0.132±0.00 N/A N/A 0.051±0.00 0.050±0.00 N/A 0.079±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000940 CIL_000940_0002 VISTA 19:44925545-45526320
CIL_0007ZR CIL_0007ZR_0002 VISTA 19:45042853-45643685
CIL_0001C6 CIL_0001C6_0003 CGP 19:45150680-45235812

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0007417 IMP central nervous system development
GO:0008284 IMP positive regulation of cell proliferation
GO:0030182 IMP neuron differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045165 IMP cell fate commitment
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048535 TAS lymph node development
GO:0048536 IMP spleen development
GO:0048645 IMP organ formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003965 tlx1 T-cell leukemia, homeobox 1 protein_coding Danio_rerio
ENSG00000107807 TLX1 T-cell leukemia homeobox 1 protein_coding Homo_sapiens

Loading