C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box and WD repeat domain containing 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107829 FBXW4 9606 - 10:101610664-101695295 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331272 FBXW4-001 101610666-101695259 protein_coding
  ENST00000457105 FBXW4-002 101624747-101695295 processed_transcript
  ENST00000470093 FBXW4-003 101610664-101626899 processed_transcript
  ENST00000482428 FBXW4-004 101611657-101613153 processed_transcript
  ENST00000489578 FBXW4-006 101673565-101676714 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331272ENST00000457105ENST00000470093
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331272 34.687±0.00 29.336±0.00 0.470±0.00 12.099±10.72 21.125±20.08 34.984±0.00 30.008±0.00 23.698±0.00 5.906±4.75 19.147±18.05 29.147±28.45 10.314±6.86 9.840±5.76 14.318±12.64
ENST00000457105 N/A N/A 6.267±0.00 8.679±1.17 2.098±0.00 7.507±0.00 1.661±0.00 5.522±0.00 5.413±0.00 N/A 4.386±0.00 10.617±7.26 21.143±0.00 15.156±0.00
ENST00000470093 N/A N/A 0.679±0.00 N/A 0.489±0.00 N/A 0.354±0.00 N/A 1.241±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZR CIL_0007ZR_0001 VISTA 10:101034855-101635629
CIL_00089J CIL_00089J_0001 VISTA 10:101185253-101786853
CIL_000942 CIL_000942_0001 VISTA 10:101206892-101808215
CIL_00099F CIL_00099F_0001 VISTA 10:101467436-102068636
CIL_00099E CIL_00099E_0001 VISTA 10:101480423-102081273
CIL_0005N9 CIL_0005N9_0001 CGP 10:101610664-101780369

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 NAS ubiquitin ligase complex
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0003674 ND molecular_function
GO:0005515 IEA protein binding
GO:0006511 NAS ubiquitin-dependent protein catabolic process
GO:0016055 IEA Wnt signaling pathway
GO:0030326 NAS embryonic limb morphogenesis
GO:0042733 IEA embryonic digit morphogenesis
GO:0051216 IEA cartilage development
GO:0060173 IEA limb development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033551 fbxw4 F-box and WD-40 domain protein 4 protein_coding Danio_rerio
ENSMUSG00000040913 Fbxw4 F-box and WD-40 domain protein 4 protein_coding Mus_musculus

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