C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107854 TNKS2 9606 + 10:91798312-91865276 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371627 TNKS2-001 91798312-91865276 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371627
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371627 8.093±0.00 6.153±0.00 0.394±0.00 5.530±2.34 4.395±0.55 5.116±1.88 2.828±1.14 3.736±0.35 4.388±1.10 7.138±1.52 4.966±0.77 7.454±3.00 8.608±3.02 6.422±2.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008L8 CIL_0008L8_0001 VISTA 10:91288732-91891966
CIL_00018M CIL_00018M_0001 CGP 10:91628442-91865276
CIL_00018L CIL_00018L_0001 CGP 10:91798312-91909483

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0000242 IDA pericentriolar material
GO:0000784 IC nuclear chromosome, telomeric region
GO:0003950 IDA:IEA NAD+ ADP-ribosyltransferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0006471 IDA protein ADP-ribosylation
GO:0016020 IEA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0019899 IPI enzyme binding
GO:0032212 IC positive regulation of telomere maintenance via telomerase
GO:0035264 IEA multicellular organism growth
GO:0040014 IEA regulation of multicellular organism growth
GO:0046872 IEA metal ion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0070198 IMP protein localization to chromosome, telomeric region
GO:0070213 IDA protein auto-ADP-ribosylation
GO:0090263 IMP positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000024811 Tnks2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 protein_coding Mus_musculus

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