C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024811 Tnks2 10090 + 19:36834232-36893477 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025729 Tnks2-001 36834232-36893477 protein_coding
  ENSMUST00000164665 Tnks2-008 36871751-36884086 protein_coding
  ENSMUST00000166677 Tnks2-003 36878507-36883081 retained_intron
  ENSMUST00000167533 Tnks2-005 36857498-36862320 retained_intron
  ENSMUST00000167724 Tnks2-006 36857881-36872463 protein_coding
  ENSMUST00000168654 Tnks2-009 36880573-36887373 retained_intron
  ENSMUST00000168656 Tnks2-002 36834404-36855937 processed_transcript
  ENSMUST00000168718 Tnks2-007 36859094-36866303 protein_coding
  ENSMUST00000168973 Tnks2-004 36849371-36855012 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025729
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025729 12.305±3.88 7.044±1.33 22.174±1.03 22.466±6.62 11.900±0.71 5.827±1.95 7.566±1.20 9.797±2.67 9.564±5.14 15.575±0.94 21.214±2.74 14.032±7.19 29.429±7.22 3.842±0.79

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008L8 CIL_0008L8_0002 VISTA 19:36386377-36989836
CIL_00018M CIL_00018M_0002 CGP 19:36731737-36893477
CIL_00018L CIL_00018L_0002 CGP 19:36834232-36919615

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 ISS protein polyubiquitination
GO:0000242 IEA pericentriolar material
GO:0000723 ISS telomere maintenance
GO:0000781 IEA chromosome, telomeric region
GO:0003950 ISS NAD+ ADP-ribosyltransferase activity
GO:0005634 IEA nucleus
GO:0005635 IEA nuclear envelope
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0006471 IEA protein ADP-ribosylation
GO:0016020 IEA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0019899 IEA enzyme binding
GO:0035264 IMP multicellular organism growth
GO:0040014 IMP regulation of multicellular organism growth
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0070198 IEA protein localization to chromosome, telomeric region
GO:0070213 ISS protein auto-ADP-ribosylation
GO:0090263 ISS positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000107854 TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 protein_coding Homo_sapiens

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