C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: colony stimulating factor 3 (granulocyte)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108342 CSF3 9606 + 17:40015361-40017813 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000225474 CSF3-001 40015444-40017813 protein_coding
  ENST00000331769 CSF3-002 40015447-40017813 protein_coding
  ENST00000394148 CSF3-004 40015467-40017057 protein_coding
  ENST00000394149 CSF3-003 40015361-40017813 protein_coding
  ENST00000479880 CSF3-005 40015447-40016943 retained_intron
  ENST00000577675 CSF3-006 40015487-40017648 protein_coding
  ENST00000579852 CSF3-007 40015446-40017758 nonsense_mediated_decay
  ENST00000582798 CSF3-009 40015435-40016162 retained_intron
  ENST00000583218 CSF3-008 40015361-40016917 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000225474ENST00000331769ENST00000394148ENST00000394149ENST00000479880ENST00000577675ENST00000579852ENST00000582798ENST00000583218
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000225474 N/A 0.132±0.00 0.776±0.00 N/A N/A N/A N/A N/A 54.076±0.00 N/A 0.202±0.14 3.315±0.00 N/A
ENST00000331769 N/A 0.299±0.00 N/A N/A 0.522±0.00 N/A N/A N/A 28.089±0.00 0.197±0.04 N/A N/A 0.450±0.00
ENST00000394148 0.077±0.00 N/A N/A N/A N/A N/A 0.306±0.00 N/A 0.200±0.00 2.740±0.00 0.821±0.00 N/A N/A
ENST00000394149 N/A N/A 0.832±0.76 N/A N/A N/A N/A N/A 19.553±0.00 N/A 0.641±0.00 0.736±0.27 0.151±0.01
ENST00000479880 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.869±0.00 N/A N/A N/A
ENST00000577675 N/A 0.156±0.00 N/A N/A N/A N/A N/A 0.544±0.00 0.150±0.00 N/A 0.295±0.00 N/A N/A
ENST00000579852 0.051±0.00 N/A N/A 0.272±0.05 N/A 0.167±0.00 N/A 0.138±0.00 61.831±0.00 N/A 1.994±0.00 0.145±0.04 N/A
ENST00000582798 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.061±0.00
ENST00000583218 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.135±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0001 VISTA 17:39768583-40372873
CIL_0002PY CIL_0002PY_0001 CGP 17:39980797-40017813
CIL_0002PX CIL_0002PX_0001 CGP 17:40015361-40061215

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005125 NAS:IEA cytokine activity
GO:0005130 TAS granulocyte colony-stimulating factor receptor binding
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006955 IEA immune response
GO:0007275 TAS multicellular organismal development
GO:0008083 IEA growth factor activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0014068 IDA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0019221 NAS cytokine-mediated signaling pathway
GO:0019899 IPI enzyme binding
GO:0030838 IDA positive regulation of actin filament polymerization
GO:0030851 NAS granulocyte differentiation
GO:0032092 IDA positive regulation of protein binding
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0042993 IDA positive regulation of transcription factor import into nucleus
GO:0045639 IEA positive regulation of myeloid cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071345 IDA cellular response to cytokine stimulus
GO:1901215 IEA negative regulation of neuron death
GO:2000251 IDA positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000038067 Csf3 colony stimulating factor 3 (granulocyte) protein_coding Mus_musculus

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