C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108344 PSMD3 9606 + 17:39980797-39997960 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264639 PSMD3-001 39980797-39997960 protein_coding
  ENST00000415039 PSMD3-003 39980836-39997611 nonsense_mediated_decay
  ENST00000485835 PSMD3-002 39992998-39996120 retained_intron
  ENST00000540504 PSMD3-005 39986609-39997955 protein_coding
  ENST00000580980 PSMD3-004 39986684-39990152 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264639ENST00000415039ENST00000485835
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264639 48.526±0.00 49.725±0.00 0.454±0.00 26.642±17.76 25.896±21.34 18.590±12.90 20.442±16.60 22.350±18.51 24.322±20.26 22.417±20.00 89.537±74.55 55.871±28.88 62.906±9.79 49.602±7.61
ENST00000415039 N/A N/A 1.108±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000485835 N/A N/A 0.529±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0001 VISTA 17:39768583-40372873
CIL_0002PR CIL_0002PR_0001 CGP 17:39962973-39997960
CIL_0002PY CIL_0002PY_0001 CGP 17:39980797-40017813

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA:IEA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005838 IEA proteasome regulatory particle
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0022624 ISS proteasome accessory complex
GO:0030234 IEA enzyme regulator activity
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042176 IEA regulation of protein catabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018124 psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 protein_coding Danio_rerio
ENSMUSG00000017221 Psmd3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 protein_coding Mus_musculus

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