C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: vitronectin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000226218 VTN-001 ENSG00000109072 9606 - 17:28367276-28370822 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartKidneyOvaryTestisENST00000226218
Transcript ID Breast Heart Kidney Ovary Testis
ENST00000226218 2.422±0.00 10.513±9.09 303.476±0.00 9.793±0.00 7.286±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000FM CIL_0000FM_0002 CGP 17:28364356-28404049

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005044 IEA scavenger receptor activity
GO:0005178 IDA integrin binding
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0006898 IEA receptor-mediated endocytosis
GO:0006955 IEA:TAS immune response
GO:0007155 TAS cell adhesion
GO:0007160 IDA cell-matrix adhesion
GO:0008201 IEA heparin binding
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0010951 IDA negative regulation of endopeptidase activity
GO:0014911 IDA positive regulation of smooth muscle cell migration
GO:0030195 IC negative regulation of blood coagulation
GO:0030198 TAS extracellular matrix organization
GO:0030247 IEA polysaccharide binding
GO:0030449 TAS regulation of complement activation
GO:0030949 TAS positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031012 IDA extracellular matrix
GO:0032092 IDA positive regulation of protein binding
GO:0033627 IDA cell adhesion mediated by integrin
GO:0035987 IDA endodermal cell differentiation
GO:0045087 TAS innate immune response
GO:0048260 IDA positive regulation of receptor-mediated endocytosis
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050840 IEA extracellular matrix binding
GO:0061302 IDA smooth muscle cell-matrix adhesion
GO:0070062 IDA extracellular vesicular exosome
GO:0071062 TAS alphav-beta3 integrin-vitronectin complex
GO:0072562 IDA blood microparticle
GO:0090303 IC positive regulation of wound healing

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000017488 Vtn-001 protein_coding Mus_musculus 0 891
ENSMUST00000128479 Vtn-002 retained_intron Mus_musculus 0 466
ENSMUST00000146997 Vtn-003 retained_intron Mus_musculus 0 276

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