C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gamma-aminobutyric acid (GABA) A receptor, alpha 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109158 GABRA4 9606 - 4:46918900-46994407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264318 GABRA4-001 46918900-46994407 protein_coding
  ENST00000502874 GABRA4-005 46971083-46993540 nonsense_mediated_decay
  ENST00000508560 GABRA4-004 46928127-46993505 nonsense_mediated_decay
  ENST00000509316 GABRA4-002 46992670-46993548 processed_transcript
  ENST00000511523 GABRA4-003 46928127-46993505 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264318ENST00000502874ENST00000508560ENST00000511523
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264318 2.563±0.37 0.007±0.00 0.016±0.00 0.853±0.22 N/A 0.042±0.00 0.009±0.01 0.004±0.00 0.002±0.00 0.067±0.00 0.014±0.00
ENST00000502874 N/A N/A N/A N/A N/A N/A 0.037±0.00 N/A N/A 0.320±0.00 0.209±0.02
ENST00000508560 N/A N/A N/A 1.815±0.15 N/A N/A N/A N/A N/A 1.317±1.11 0.223±0.00
ENST00000511523 N/A 0.012±0.00 N/A N/A 0.062±0.00 N/A N/A N/A N/A N/A 0.158±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002YV CIL_0002YV_0001 CGP 4:46734827-46994407
CIL_0001N0 CIL_0001N0_0001 CGP 4:46918900-47426444

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004890 IEA GABA-A receptor activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005254 IEA chloride channel activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS:IEA transport
GO:0006811 IEA ion transport
GO:0007214 IEA gamma-aminobutyric acid signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007417 IEA central nervous system development
GO:0008503 TAS benzodiazepine receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0034220 TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0045211 IEA postsynaptic membrane
GO:0055085 TAS transmembrane transport
GO:1902476 IEA chloride transmembrane transport
GO:2001023 IEA regulation of response to drug

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013389 GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 protein_coding Danio_rerio
ENSMUSG00000029211 Gabra4 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 protein_coding Mus_musculus

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