C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neurexin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110076 NRXN2 9606 - 11:64606174-64723188 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265459 NRXN2-201 64606176-64723188 protein_coding
  ENST00000301894 NRXN2-003 64606174-64643315 protein_coding
  ENST00000377551 NRXN2-001 64606174-64713911 protein_coding
  ENST00000377559 NRXN2-002 64606174-64723188 protein_coding
  ENST00000409571 NRXN2-015 64606177-64713943 protein_coding
  ENST00000417749 NRXN2-012 64667667-64712981 protein_coding
  ENST00000423049 NRXN2-006 64622753-64642686 protein_coding
  ENST00000437746 NRXN2-013 64668482-64713097 protein_coding
  ENST00000442300 NRXN2-011 64667438-64712745 protein_coding
  ENST00000464307 NRXN2-005 64606174-64623996 retained_intron
  ENST00000466324 NRXN2-014 64675177-64713943 retained_intron
  ENST00000467055 NRXN2-007 64630405-64637445 processed_transcript
  ENST00000475737 NRXN2-004 64607044-64622796 processed_transcript
  ENST00000486057 NRXN2-009 64651279-64656120 processed_transcript
  ENST00000487484 NRXN2-008 64630486-64643486 processed_transcript
  ENST00000496291 NRXN2-010 64660470-64661378 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301894ENST00000377559ENST00000409571ENST00000417749ENST00000423049ENST00000464307ENST00000466324ENST00000467055ENST00000475737ENST00000486057ENST00000487484ENST00000496291
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301894 1.346±0.00 N/A 18.562±0.00 N/A 7.234±0.00 0.090±0.00 1.555±0.00 2.252±0.00 0.231±0.20 N/A 12.322±13.36 0.478±0.10 7.337±2.87
ENST00000377559 N/A N/A N/A 0.022±0.00 N/A N/A N/A N/A 0.015±0.00 N/A 0.023±0.00 N/A N/A
ENST00000409571 N/A N/A 1.749±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.131±0.00 N/A
ENST00000417749 N/A N/A N/A N/A 1.128±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000423049 3.816±0.00 N/A N/A 1.569±0.00 N/A N/A N/A N/A N/A N/A 15.003±14.63 N/A 18.369±0.00
ENST00000464307 N/A 0.023±0.00 N/A N/A 0.073±0.00 0.045±0.00 0.194±0.00 N/A N/A N/A N/A N/A N/A
ENST00000466324 N/A N/A N/A N/A N/A N/A N/A N/A 0.057±0.00 N/A N/A N/A N/A
ENST00000467055 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.450±0.00 N/A N/A
ENST00000475737 N/A 0.570±0.00 N/A 0.285±0.00 11.692±0.00 0.053±0.00 3.793±0.00 N/A 0.730±0.00 0.958±0.00 0.394±0.00 N/A N/A
ENST00000486057 N/A N/A N/A N/A 0.317±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000487484 N/A N/A N/A N/A N/A N/A N/A N/A 1.256±0.00 N/A N/A N/A N/A
ENST00000496291 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.305±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005J6 CIL_0005J6_0002 CGP 11:64606174-64745456

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005246 ISS calcium channel regulator activity
GO:0005515 IEA protein binding
GO:0007158 TAS neuron cell-cell adhesion
GO:0007268 ISS synaptic transmission
GO:0007269 ISS neurotransmitter secretion
GO:0007416 ISS synapse assembly
GO:0016021 IEA integral component of membrane
GO:0030534 IMP adult behavior
GO:0035176 IMP social behavior
GO:0042297 IMP vocal learning
GO:0046872 IEA metal ion binding
GO:0050839 ISS cell adhesion molecule binding
GO:0071625 IMP vocalization behavior
GO:0097104 ISS postsynaptic membrane assembly
GO:0097109 ISS neuroligin family protein binding
GO:0097116 ISS gephyrin clustering
GO:0097118 ISS neuroligin clustering
GO:0097119 ISS postsynaptic density protein 95 clustering

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061454 nrxn2a neurexin 2a protein_coding Danio_rerio
ENSDARG00000063606 NRXN2 (2 of 2) neurexin 2 protein_coding Danio_rerio
ENSMUSG00000033768 Nrxn2 neurexin II protein_coding Mus_musculus

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