C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pre-mRNA processing factor 19
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110107 PRPF19 9606 - 11:60890730-60906588 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000227524 PRPF19-001 60890730-60906588 protein_coding
  ENST00000535326 PRPF19-007 60890747-60898931 protein_coding
  ENST00000539180 PRPF19-005 60897880-60898469 retained_intron
  ENST00000539960 PRPF19-004 60897550-60899215 retained_intron
  ENST00000540473 PRPF19-006 60890736-60902414 protein_coding
  ENST00000541371 PRPF19-003 60898541-60906569 protein_coding
  ENST00000546152 PRPF19-002 60901499-60906541 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227524ENST00000535326ENST00000539960ENST00000541371
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227524 20.590±0.00 45.909±0.00 37.195±23.74 25.866±0.00 13.883±9.63 6.776±6.39 35.594±0.00 15.970±13.84 19.834±0.00 17.108±15.30 51.334±28.16 56.333±7.43 32.527±2.52
ENST00000535326 20.327±0.00 69.426±0.00 41.287±0.00 33.564±0.00 24.256±0.00 N/A N/A N/A 6.737±0.00 N/A 36.672±0.00 N/A 55.914±0.00
ENST00000539960 N/A N/A N/A 3.865±0.00 2.230±0.00 N/A N/A 2.193±0.00 3.072±0.00 5.603±0.00 5.692±0.00 N/A N/A
ENST00000541371 N/A N/A 6.932±0.00 2.752±0.00 N/A N/A N/A N/A 3.181±0.00 1.964±0.00 3.703±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0000244 IDA spliceosomal tri-snRNP complex assembly
GO:0000245 IMP spliceosomal complex assembly
GO:0000398 IC mRNA splicing, via spliceosome
GO:0000974 IDA Prp19 complex
GO:0001833 IEA inner cell mass cell proliferation
GO:0003677 IEA DNA binding
GO:0004842 IDA:IEA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005662 IDA DNA replication factor A complex
GO:0005737 IDA cytoplasm
GO:0005811 IEA lipid particle
GO:0005856 IEA cytoskeleton
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0008610 IEA lipid biosynthetic process
GO:0010498 IMP proteasomal protein catabolic process
GO:0016020 IDA membrane
GO:0016567 IEA protein ubiquitination
GO:0016607 IDA nuclear speck
GO:0034450 IDA ubiquitin-ubiquitin ligase activity
GO:0034613 IMP cellular protein localization
GO:0035861 IDA site of double-strand break
GO:0042802 IPI identical protein binding
GO:0045665 IEA negative regulation of neuron differentiation
GO:0048026 IEA positive regulation of mRNA splicing, via spliceosome
GO:0048711 IEA positive regulation of astrocyte differentiation
GO:0061630 IMP ubiquitin protein ligase activity
GO:0070534 IMP protein K63-linked ubiquitination
GO:0071013 IDA catalytic step 2 spliceosome
GO:0072422 IMP signal transduction involved in DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015239 prp19 PRP19/PSO4 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000024735 Prpf19 PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) protein_coding Mus_musculus

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