C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024735 Prpf19 10090 + 19:10895231-10909559 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025642 Prpf19-001 10895231-10905532 protein_coding
  ENSMUST00000178868 Prpf19-003 10898645-10905506 processed_transcript
  ENSMUST00000179297 Prpf19-002 10895414-10909559 protein_coding
  ENSMUST00000186416 Prpf19-004 10895277-10897911 retained_intron
  ENSMUST00000187751 Prpf19-005 10895282-10898260 retained_intron
  ENSMUST00000190275 Prpf19-006 10895373-10899367 retained_intron
  ENSMUST00000191092 Prpf19-008 10899369-10902760 retained_intron
  ENSMUST00000191552 Prpf19-007 10900282-10900993 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025642ENSMUST00000178868
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025642 92.065±37.48 168.497±20.75 52.102±9.34 85.283±49.13 88.955±15.19 69.906±15.72 120.548±33.14 57.950±5.48 72.820±17.34 69.159±3.66 86.362±9.63 159.523±72.90 48.120±28.86 26.784±11.17
ENSMUST00000178868 N/A N/A N/A 38.136±0.00 24.344±0.00 N/A N/A N/A N/A N/A N/A 33.958±4.12 23.524±7.28 2.702±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IEA protein polyubiquitination
GO:0000244 ISS spliceosomal tri-snRNP complex assembly
GO:0000245 IEA spliceosomal complex assembly
GO:0000398 ISS mRNA splicing, via spliceosome
GO:0000974 ISS Prp19 complex
GO:0001833 IMP inner cell mass cell proliferation
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005662 ISS DNA replication factor A complex
GO:0005681 ISA spliceosomal complex
GO:0005737 IDA cytoplasm
GO:0005811 IDA lipid particle
GO:0005856 IEA cytoskeleton
GO:0006303 ISS double-strand break repair via nonhomologous end joining
GO:0008610 IDA lipid biosynthetic process
GO:0010498 IMP proteasomal protein catabolic process
GO:0016020 IEA membrane
GO:0016607 ISS nuclear speck
GO:0034450 IEA ubiquitin-ubiquitin ligase activity
GO:0034613 ISS cellular protein localization
GO:0035861 ISS site of double-strand break
GO:0042802 IEA identical protein binding
GO:0045665 IDA negative regulation of neuron differentiation
GO:0045666 ISA positive regulation of neuron differentiation
GO:0048026 IMP positive regulation of mRNA splicing, via spliceosome
GO:0048711 IDA positive regulation of astrocyte differentiation
GO:0061630 ISS ubiquitin protein ligase activity
GO:0070534 ISS protein K63-linked ubiquitination
GO:0071013 IEA catalytic step 2 spliceosome
GO:0072422 ISS signal transduction involved in DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015239 prp19 PRP19/PSO4 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000110107 PRPF19 pre-mRNA processing factor 19 protein_coding Homo_sapiens

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