C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pre-mRNA processing factor 19
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000227524 PRPF19-001 ENSG00000110107 9606 - 11:60890730-60906588 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227524
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227524 20.590±0.00 45.909±0.00 37.195±23.74 25.866±0.00 13.883±9.63 6.776±6.39 35.594±0.00 15.970±13.84 19.834±0.00 17.108±15.30 51.334±28.16 56.333±7.43 32.527±2.52

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0000244 IDA spliceosomal tri-snRNP complex assembly
GO:0000245 IMP spliceosomal complex assembly
GO:0000398 IC mRNA splicing, via spliceosome
GO:0000974 IDA Prp19 complex
GO:0001833 IEA inner cell mass cell proliferation
GO:0003677 IEA DNA binding
GO:0004842 IDA:IEA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005662 IDA DNA replication factor A complex
GO:0005737 IDA cytoplasm
GO:0005811 IEA lipid particle
GO:0005856 IEA cytoskeleton
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0008610 IEA lipid biosynthetic process
GO:0010498 IMP proteasomal protein catabolic process
GO:0016020 IDA membrane
GO:0016567 IEA protein ubiquitination
GO:0016607 IDA nuclear speck
GO:0034450 IDA ubiquitin-ubiquitin ligase activity
GO:0034613 IMP cellular protein localization
GO:0035861 IDA site of double-strand break
GO:0042802 IPI identical protein binding
GO:0045665 IEA negative regulation of neuron differentiation
GO:0048026 IEA positive regulation of mRNA splicing, via spliceosome
GO:0048711 IEA positive regulation of astrocyte differentiation
GO:0061630 IMP ubiquitin protein ligase activity
GO:0070534 IMP protein K63-linked ubiquitination
GO:0071013 IDA catalytic step 2 spliceosome
GO:0072422 IMP signal transduction involved in DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025642 Prpf19-001 protein_coding Mus_musculus 0 2169
ENSMUST00000178868 Prpf19-003 processed_transcript Mus_musculus 0 1749
ENSMUST00000179297 Prpf19-002 protein_coding Mus_musculus 0 1749
ENSMUST00000163185 Gm7701-001 processed_pseudogene Mus_musculus 0 1498
ENSMUST00000191092 Prpf19-008 retained_intron Mus_musculus 0 645
ENSMUST00000190275 Prpf19-006 retained_intron Mus_musculus 0 568
ENSMUST00000187751 Prpf19-005 retained_intron Mus_musculus 0 392

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