C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110719 TCIRG1 9606 + 11:68039016-68050895 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265686 TCIRG1-001 68039016-68050895 protein_coding
  ENST00000524598 TCIRG1-011 68039082-68044264 protein_coding
  ENST00000524870 TCIRG1-005 68049148-68050220 retained_intron
  ENST00000525516 TCIRG1-015 68047474-68048332 retained_intron
  ENST00000525724 TCIRG1-009 68043789-68050878 retained_intron
  ENST00000527530 TCIRG1-013 68043323-68044235 retained_intron
  ENST00000528981 TCIRG1-012 68044235-68048927 nonsense_mediated_decay
  ENST00000529364 TCIRG1-014 68043368-68047798 protein_coding
  ENST00000529657 TCIRG1-002 68039106-68043593 protein_coding
  ENST00000530063 TCIRG1-007 68050046-68050821 protein_coding
  ENST00000530449 TCIRG1-006 68050053-68050647 retained_intron
  ENST00000530802 TCIRG1-008 68050283-68050821 processed_transcript
  ENST00000532635 TCIRG1-016 68042980-68050895 protein_coding
  ENST00000533005 TCIRG1-004 68044289-68050868 retained_intron
  ENST00000533947 TCIRG1-003 68039115-68043590 retained_intron
  ENST00000534673 TCIRG1-010 68039029-68044204 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000265686ENST00000525724ENST00000528981ENST00000532635ENST00000533005
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000265686 14.426±0.00 15.305±0.00 10.073±0.00 9.474±0.00 2.383±0.00 4.945±0.00 3.542±0.00 9.719±6.36 N/A 15.684±0.00 8.889±4.37
ENST00000525724 16.221±0.00 13.326±0.00 10.458±0.00 7.629±0.00 2.622±0.00 5.302±1.38 11.140±0.00 17.722±0.00 N/A 15.522±2.37 12.613±4.76
ENST00000528981 N/A N/A N/A N/A N/A N/A N/A N/A 5.490±0.00 16.310±0.00 N/A
ENST00000532635 N/A 9.242±0.00 N/A N/A 1.705±0.00 N/A N/A 11.564±0.00 1.461±0.00 14.161±0.00 7.278±2.55
ENST00000533005 N/A 13.743±0.00 N/A N/A N/A N/A N/A 12.921±0.00 N/A 16.552±0.00 7.077±1.86

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000220 IEA vacuolar proton-transporting V-type ATPase, V0 domain
GO:0005215 TAS transporter activity
GO:0005739 IEA mitochondrion
GO:0005765 IDA lysosomal membrane
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006879 TAS cellular iron ion homeostasis
GO:0006968 TAS cellular defense response
GO:0008284 TAS positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0010008 TAS endosome membrane
GO:0015078 IEA hydrogen ion transmembrane transporter activity
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0015992 TAS proton transport
GO:0016324 IDA apical plasma membrane
GO:0030670 TAS phagocytic vesicle membrane
GO:0033179 IEA proton-transporting V-type ATPase, V0 domain
GO:0033572 TAS transferrin transport
GO:0051701 TAS interaction with host
GO:0055085 TAS transmembrane transport
GO:0090382 TAS phagosome maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016835 tcirg1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 protein_coding Danio_rerio
ENSDARG00000076003 TCIRG1 (2 of 2) T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 protein_coding Danio_rerio
ENSMUSG00000001750 Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 protein_coding Mus_musculus

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