C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: bridging integrator 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110934 BIN2 9606 - 12:51281038-51324668 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000267012 BIN2-201 51281039-51324154 protein_coding
  ENST00000452142 BIN2-004 51281038-51324154 protein_coding
  ENST00000544402 BIN2-002 51281282-51324668 protein_coding
  ENST00000603177 BIN2-009 51292162-51297368 retained_intron
  ENST00000603260 BIN2-007 51322585-51324085 processed_transcript
  ENST00000604560 BIN2-005 51281038-51324115 protein_coding
  ENST00000604702 BIN2-006 51322748-51324093 processed_transcript
  ENST00000605039 BIN2-003 51281038-51324154 retained_intron
  ENST00000605423 BIN2-010 51302717-51324142 nonsense_mediated_decay
  ENST00000605819 BIN2-008 51292202-51297373 retained_intron
  ENST00000615107 BIN2-001 51281038-51324198 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000267012ENST00000452142ENST00000544402ENST00000603260ENST00000604560ENST00000605039ENST00000605423ENST00000615107
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000267012 2.740±0.00 12.642±0.00 N/A 0.829±0.34 0.785±0.00 N/A 0.437±0.37 0.252±0.00 1.168±0.00 6.505±0.00 N/A 0.843±0.55 8.917±2.03 4.139±0.14
ENST00000452142 N/A N/A N/A N/A N/A N/A N/A N/A 0.193±0.00 N/A N/A N/A N/A N/A
ENST00000544402 N/A N/A 0.112±0.00 N/A N/A 0.389±0.00 N/A 0.410±0.21 0.270±0.00 2.180±0.00 0.121±0.00 0.521±0.00 9.494±7.44 7.457±0.00
ENST00000603260 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.389±0.00
ENST00000604560 0.506±0.00 N/A N/A 0.199±0.00 0.522±0.32 0.798±0.00 0.322±0.00 0.758±0.00 0.342±0.00 1.288±0.00 N/A 0.471±0.00 N/A N/A
ENST00000605039 N/A N/A N/A 0.199±0.00 N/A N/A N/A N/A N/A 0.604±0.00 N/A 0.168±0.01 N/A N/A
ENST00000605423 N/A N/A N/A 1.154±0.00 N/A N/A N/A N/A N/A N/A 0.074±0.00 N/A N/A N/A
ENST00000615107 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.846±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003K2 CIL_0003K2_0001 CGP 12:51244558-51324668
CIL_0006JT CIL_0006JT_0001 CGP 12:51281038-51346679

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001891 IDA phagocytic cup
GO:0002102 IDA podosome
GO:0005515 IPI:IEA protein binding
GO:0005543 IDA phospholipid binding
GO:0005737 IEA cytoplasm
GO:0006911 IMP phagocytosis, engulfment
GO:0030054 IEA cell junction
GO:0042995 IEA cell projection
GO:0060326 IMP cell chemotaxis
GO:0071800 IMP podosome assembly
GO:0097320 IDA membrane tubulation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003219 bin2a bridging integrator 2a protein_coding Danio_rerio
ENSDARG00000010255 bin2b bridging integrator 2b protein_coding Danio_rerio
ENSMUSG00000098112 Bin2 bridging integrator 2 protein_coding Mus_musculus

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