C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: keratin 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111057 KRT18 9606 + 12:52948871-52952901 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000388835 KRT18-002 52948964-52952901 protein_coding
  ENST00000388837 KRT18-201 52948871-52952900 protein_coding
  ENST00000546656 KRT18-005 52951496-52952278 retained_intron
  ENST00000548015 KRT18-004 52949805-52951645 retained_intron
  ENST00000548496 KRT18-006 52951742-52952815 retained_intron
  ENST00000549078 KRT18-003 52949127-52952872 retained_intron
  ENST00000550600 KRT18-001 52948886-52952812 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000388835ENST00000388837ENST00000546656
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000388835 7.190±0.00 4.135±0.00 2.929±0.00 N/A 25.047±0.00 32.800±4.94 N/A 42.380±0.00 82.351±74.60 99.876±95.47 0.785±0.00 188.216±210.92 772.871±0.00 9.241±2.32
ENST00000388837 N/A 3.621±0.00 9.546±0.00 0.640±0.51 34.365±10.55 45.842±10.70 0.953±0.00 61.556±24.06 11.338±0.00 10.708±0.00 0.654±0.36 63.883±59.75 785.368±228.96 13.904±0.00
ENST00000546656 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.750±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038V CIL_00038V_0001 CGP 12:52837804-52949954
CIL_0006T8 CIL_0006T8_0001 CGP 12:52897187-52952901
CIL_0006TF CIL_0006TF_0001 CGP 12:52948871-53042209

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005815 IDA microtubule organizing center
GO:0005882 IDA:IEA intermediate filament
GO:0007049 IEA cell cycle
GO:0009653 TAS anatomical structure morphogenesis
GO:0016032 IEA viral process
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0034451 IDA centriolar satellite
GO:0043000 IDA Golgi to plasma membrane CFTR protein transport
GO:0043066 IDA negative regulation of apoptotic process
GO:0044822 IDA poly(A) RNA binding
GO:0045095 IDA keratin filament
GO:0045104 IDA intermediate filament cytoskeleton organization
GO:0070062 IDA extracellular vesicular exosome
GO:0071944 IEA cell periphery
GO:0097110 IPI scaffold protein binding
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:0097284 IEA hepatocyte apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000023043 Krt18 keratin 18 protein_coding Mus_musculus

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