C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: general transcription factor IIH, polypeptide 3, 34kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111358 GTF2H3 9606 + 12:123633739-123662606 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000228955 GTF2H3-002 123633829-123660829 protein_coding
  ENST00000536375 GTF2H3-011 123633845-123660212 protein_coding
  ENST00000537368 GTF2H3-009 123633829-123651156 retained_intron
  ENST00000537695 GTF2H3-010 123633833-123654970 retained_intron
  ENST00000538533 GTF2H3-013 123639264-123659830 protein_coding
  ENST00000538845 GTF2H3-003 123633829-123655796 protein_coding
  ENST00000539429 GTF2H3-014 123659363-123660628 retained_intron
  ENST00000539994 GTF2H3-004 123633829-123654998 protein_coding
  ENST00000542279 GTF2H3-007 123633828-123659584 nonsense_mediated_decay
  ENST00000543005 GTF2H3-006 123633829-123648396 retained_intron
  ENST00000543154 GTF2H3-008 123648051-123660232 protein_coding
  ENST00000543341 GTF2H3-001 123633829-123662606 protein_coding
  ENST00000543415 GTF2H3-012 123639263-123660250 nonsense_mediated_decay
  ENST00000618160 GTF2H3-201 123633739-123662603 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000228955ENST00000543341ENST00000618160
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000228955 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.561±0.00 N/A N/A
ENST00000543341 3.141±0.00 8.994±0.00 3.527±1.86 3.328±0.00 2.509±0.00 1.588±0.61 4.047±0.00 2.369±1.33 1.638±0.00 5.365±0.72 3.369±0.48 4.022±0.47
ENST00000618160 N/A N/A N/A N/A N/A N/A 1.355±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000395 CIL_000395_0001 CGP 12:123602077-123633766
CIL_00006O CIL_00006O_0002 CGP 12:123620406-123662606

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000439 IEA core TFIIH complex
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0003684 TAS damaged DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0004672 IDA protein kinase activity
GO:0005654 TAS nucleoplasm
GO:0005675 IDA holo TFIIH complex
GO:0006200 IDA ATP catabolic process
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS:IEA nucleotide-excision repair
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006360 TAS transcription from RNA polymerase I promoter
GO:0006361 TAS transcription initiation from RNA polymerase I promoter
GO:0006362 TAS transcription elongation from RNA polymerase I promoter
GO:0006363 TAS termination of RNA polymerase I transcription
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0006412 TAS translation
GO:0006468 IDA protein phosphorylation
GO:0008094 IDA DNA-dependent ATPase activity
GO:0008135 TAS translation factor activity, nucleic acid binding
GO:0008353 IDA RNA polymerase II carboxy-terminal domain kinase activity
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0046872 IEA metal ion binding
GO:0047485 IPI protein N-terminus binding
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067560 gtf2h3 general transcription factor IIH, polypeptide 3 protein_coding Danio_rerio
ENSMUSG00000029387 Gtf2h3 general transcription factor IIH, polypeptide 3 protein_coding Mus_musculus

Loading