C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: general transcription factor IIH, polypeptide 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029387 Gtf2h3 10090 + 5:124579140-124597680 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031333 Gtf2h3-001 124579140-124597680 protein_coding
  ENSMUST00000126466 Gtf2h3-004 124579166-124592627 processed_transcript
  ENSMUST00000142746 Gtf2h3-002 124590379-124596587 retained_intron
  ENSMUST00000143810 Gtf2h3-005 124594265-124595605 retained_intron
  ENSMUST00000153436 Gtf2h3-003 124583847-124595596 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031333ENSMUST00000126466ENSMUST00000142746ENSMUST00000153436
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031333 N/A N/A 2.733±0.45 2.393±1.31 N/A N/A N/A 1.738±0.00 3.223±1.64 1.661±0.00 1.543±0.32 2.718±0.90 4.507±1.04 0.637±0.33
ENSMUST00000126466 N/A N/A 13.357±2.12 10.104±2.84 N/A N/A 5.971±1.18 8.430±0.00 10.476±8.37 6.743±0.00 3.121±0.27 6.933±0.00 13.291±3.46 3.661±1.44
ENSMUST00000142746 6.689±1.61 8.971±5.29 8.584±1.53 9.576±3.83 9.940±4.39 4.221±1.34 4.352±2.60 3.285±0.91 6.239±3.93 8.317±0.77 1.626±0.50 9.702±5.54 7.390±1.82 1.958±0.41
ENSMUST00000153436 N/A N/A N/A N/A 12.178±2.79 N/A N/A N/A N/A N/A 2.135±0.00 9.843±1.19 9.523±2.68 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00006O CIL_00006O_0003 CGP 5:124570213-124597680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000439 IEA core TFIIH complex
GO:0004672 ISS protein kinase activity
GO:0005675 ISS holo TFIIH complex
GO:0006200 IEA ATP catabolic process
GO:0006289 IEA nucleotide-excision repair
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0008094 ISS DNA-dependent ATPase activity
GO:0008353 ISS RNA polymerase II carboxy-terminal domain kinase activity
GO:0046872 IEA metal ion binding
GO:0047485 IEA protein N-terminus binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067560 gtf2h3 general transcription factor IIH, polypeptide 3 protein_coding Danio_rerio
ENSG00000111358 GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa protein_coding Homo_sapiens

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