C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Nanog homeobox
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111704 NANOG 9606 + 12:7787794-7799141 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229307 NANOG-001 7789396-7799141 protein_coding
  ENST00000526286 NANOG-002 7789615-7795095 protein_coding
  ENST00000526434 NANOG-003 7789433-7793212 processed_transcript
  ENST00000541267 NANOG-004 7787794-7794808 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000229307ENST00000526286ENST00000526434
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000229307 0.048±0.00 0.201±0.00 0.012±0.00 0.135±0.00 0.113±0.00 0.107±0.00 0.034±0.03 0.085±0.00 0.038±0.02 0.075±0.00 0.088±0.00 0.042±0.03 0.017±0.00 0.266±0.13
ENST00000526286 N/A N/A N/A 0.083±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000526434 N/A N/A N/A N/A N/A N/A N/A N/A 0.185±0.07 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001C CIL_00001C_0001 CGP 12:7787794-7891148

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001158 IEA enhancer sequence-specific DNA binding
GO:0001710 IEA mesodermal cell fate commitment
GO:0001714 IDA endodermal cell fate specification
GO:0003677 IDA:IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IC nucleus
GO:0005654 IEA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0008283 IMP cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0008406 IEA gonad development
GO:0009880 IEA embryonic pattern specification
GO:0010033 IEA response to organic substance
GO:0010454 IEA negative regulation of cell fate commitment
GO:0010468 IMP regulation of gene expression
GO:0017145 IEA stem cell division
GO:0019827 IEP stem cell maintenance
GO:0030154 IEP cell differentiation
GO:0030514 IEA negative regulation of BMP signaling pathway
GO:0032526 IEA response to retinoic acid
GO:0035019 IMP somatic stem cell maintenance
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045595 IMP regulation of cell differentiation
GO:0045596 IEA negative regulation of cell differentiation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048863 IEA stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000012396 Nanog Nanog homeobox protein_coding Mus_musculus

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