C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Nanog homeobox
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000012396 Nanog 10090 + 6:122707489-122714633 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000012540 Nanog-001 122707568-122714633 protein_coding
  ENSMUST00000112580 Nanog-002 122707565-122714633 protein_coding
  ENSMUST00000112581 Nanog-003 122707489-122714633 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000012540ENSMUST00000112580ENSMUST00000112581
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000012540 0.134±0.00 0.034±0.00 0.038±0.00 N/A N/A N/A N/A N/A 0.136±0.01 0.166±0.05 0.025±0.00 0.050±0.00
ENSMUST00000112580 0.115±0.13 N/A 0.047±0.00 N/A N/A 0.002±0.00 N/A 0.008±0.01 N/A 0.008±0.00 N/A 0.075±0.00
ENSMUST00000112581 0.019±0.00 0.038±0.03 0.037±0.00 0.121±0.03 0.056±0.02 0.014±0.00 0.031±0.01 0.021±0.01 0.086±0.05 0.145±0.08 0.070±0.02 0.072±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001C CIL_00001C_0002 CGP 6:122707489-122801640

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001710 IGI mesodermal cell fate commitment
GO:0001714 ISO endodermal cell fate specification
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003714 IMP transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IEA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008283 IEA cell proliferation
GO:0008284 IDA positive regulation of cell proliferation
GO:0008406 IEP gonad development
GO:0009880 IEP embryonic pattern specification
GO:0010033 IDA response to organic substance
GO:0010454 IDA negative regulation of cell fate commitment
GO:0010468 IEA regulation of gene expression
GO:0017145 IDA stem cell division
GO:0019827 IMP stem cell maintenance
GO:0030154 IEA cell differentiation
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0032526 IDA response to retinoic acid
GO:0035019 IEA somatic stem cell maintenance
GO:0042664 TAS negative regulation of endodermal cell fate specification
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045595 IEA regulation of cell differentiation
GO:0045596 IDA negative regulation of cell differentiation
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045931 IDA positive regulation of mitotic cell cycle
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048863 IMP stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000111704 NANOG Nanog homeobox protein_coding Homo_sapiens

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