C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: opioid receptor, mu 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112038 OPRM1 9606 + 6:154010496-154246867 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229768 OPRM1-012 154039495-154093520 protein_coding
  ENST00000330432 OPRM1-001 154039308-154119459 protein_coding
  ENST00000337049 OPRM1-008 154039495-154246867 protein_coding
  ENST00000360422 OPRM1-201 154039102-154091938 protein_coding
  ENST00000414028 OPRM1-016 154039495-154109018 protein_coding
  ENST00000419506 OPRM1-013 154039495-154107652 protein_coding
  ENST00000428397 OPRM1-002 154039349-154091593 protein_coding
  ENST00000434900 OPRM1-003 154010501-154118754 protein_coding
  ENST00000435918 OPRM1-017 154039495-154109018 protein_coding
  ENST00000452687 OPRM1-010 154039456-154110453 protein_coding
  ENST00000518759 OPRM1-006 154010501-154118809 protein_coding
  ENST00000519083 OPRM1-015 154039495-154109018 nonsense_mediated_decay
  ENST00000519613 OPRM1-018 154083490-154118713 processed_transcript
  ENST00000520282 OPRM1-004 154010496-154089879 protein_coding
  ENST00000520708 OPRM1-005 154010501-154118809 protein_coding
  ENST00000521106 OPRM1-023 154089826-154091957 processed_transcript
  ENST00000522236 OPRM1-020 154086507-154118969 protein_coding
  ENST00000522382 OPRM1-021 154089762-154091938 processed_transcript
  ENST00000522555 OPRM1-019 154086507-154118969 protein_coding
  ENST00000522739 OPRM1-011 154039475-154118807 nonsense_mediated_decay
  ENST00000523520 OPRM1-007 154039364-154074458 processed_transcript
  ENST00000524150 OPRM1-009 154039479-154246860 nonsense_mediated_decay
  ENST00000524163 OPRM1-014 154039495-154107652 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002QK CIL_0002QK_0002 CGP 6:153004459-154246867
CIL_00055K CIL_00055K_0001 CGP 6:154010496-154356792

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001965 IDA G-protein alpha-subunit binding
GO:0002438 IEA acute inflammatory response to antigenic stimulus
GO:0004930 ISS:IEA G-protein coupled receptor activity
GO:0004979 IMP beta-endorphin receptor activity
GO:0004985 IEA opioid receptor activity
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005783 TAS endoplasmic reticulum
GO:0005794 TAS Golgi apparatus
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005925 IEA focal adhesion
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007191 IEA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007194 ISS negative regulation of adenylate cyclase activity
GO:0007200 ISS phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007600 NAS sensory perception
GO:0007626 IEA locomotory behavior
GO:0008285 TAS negative regulation of cell proliferation
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019233 ISS sensory perception of pain
GO:0019904 IEA protein domain specific binding
GO:0030425 IEA dendrite
GO:0031005 IEA filamin binding
GO:0031635 IEA adenylate cyclase-inhibiting opioid receptor signaling pathway
GO:0031681 IEA G-protein beta-subunit binding
GO:0032094 IEA response to food
GO:0032100 IEA positive regulation of appetite
GO:0032496 IEA response to lipopolysaccharide
GO:0032590 IEA dendrite membrane
GO:0032839 IEA dendrite cytoplasm
GO:0033554 IMP cellular response to stress
GO:0038003 IEA opioid receptor signaling pathway
GO:0038047 ISS morphine receptor activity
GO:0042060 IEA wound healing
GO:0042220 IEA response to cocaine
GO:0042383 IEA sarcolemma
GO:0043204 IEA perikaryon
GO:0043278 IEA response to morphine
GO:0043950 IDA positive regulation of cAMP-mediated signaling
GO:0043951 IDA negative regulation of cAMP-mediated signaling
GO:0045019 IDA negative regulation of nitric oxide biosynthetic process
GO:0045121 IEA membrane raft
GO:0045429 IDA positive regulation of nitric oxide biosynthetic process
GO:0048149 IMP behavioral response to ethanol
GO:0050769 ISS positive regulation of neurogenesis
GO:0051481 IDA negative regulation of cytosolic calcium ion concentration
GO:0051930 IEA regulation of sensory perception of pain
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0061358 IMP negative regulation of Wnt protein secretion
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070588 ISS calcium ion transmembrane transport
GO:0070848 IEA response to growth factor
GO:0071315 IEA cellular response to morphine
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039434 oprm1 opioid receptor, mu 1 protein_coding Danio_rerio
ENSMUSG00000000766 Oprm1 opioid receptor, mu 1 protein_coding Mus_musculus

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