C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAD1 checkpoint DNA exonuclease
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113456 RAD1 9606 - 5:34905264-34918989 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000325577 RAD1-002 34908554-34915548 nonsense_mediated_decay
  ENST00000341754 RAD1-003 34908172-34918989 protein_coding
  ENST00000382038 RAD1-001 34905264-34916766 protein_coding
  ENST00000506311 RAD1-004 34914477-34915504 retained_intron
  ENST00000511456 RAD1-006 34911618-34915517 nonsense_mediated_decay
  ENST00000512192 RAD1-007 34913871-34914801 retained_intron
  ENST00000513914 RAD1-005 34908655-34915615 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000325577ENST00000341754ENST00000382038ENST00000513914
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000325577 3.364±0.00 3.662±0.00 3.226±0.43 4.057±0.00 5.130±0.00 3.670±0.00 2.771±0.00 3.723±0.60 2.267±1.13 7.156±0.00 6.856±0.51 8.904±0.00
ENST00000341754 N/A 2.350±0.00 N/A 1.098±0.00 1.152±0.00 1.503±0.00 1.860±0.00 1.576±0.00 1.146±0.00 2.298±0.00 N/A N/A
ENST00000382038 N/A 1.059±0.00 N/A N/A 1.503±0.00 0.849±0.00 0.432±0.00 N/A 0.465±0.00 1.192±0.00 N/A 2.005±0.62
ENST00000513914 N/A N/A N/A N/A 2.740±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0000738 IEA DNA catabolic process, exonucleolytic
GO:0003684 TAS damaged DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 IDA nucleoplasm
GO:0005694 IDA chromosome
GO:0006260 TAS DNA replication
GO:0006281 IEA DNA repair
GO:0006974 TAS cellular response to DNA damage stimulus
GO:0008408 IDA 3'-5' exonuclease activity
GO:0008853 IEA exodeoxyribonuclease III activity
GO:0021762 IEP substantia nigra development
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0051598 IGI meiotic recombination checkpoint
GO:0071479 IDA cellular response to ionizing radiation
GO:0090305 IDA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040559 rad1 RAD1 homolog (S. pombe) protein_coding Danio_rerio
ENSMUSG00000022248 Rad1 RAD1 homolog (S. pombe) protein_coding Mus_musculus

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