Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	RAD1 checkpoint DNA exonuclease
ENST00000325577	RAD1-002	ENSG00000113456	9606	-	5:34908554-34915548	nonsense_mediated_decay

Expression Patterns

Transcript ID	Adipose	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000325577	3.364±0.00	3.662±0.00	3.226±0.43	4.057±0.00	5.130±0.00	3.670±0.00	2.771±0.00	3.723±0.60	2.267±1.13	7.156±0.00	6.856±0.51	8.904±0.00

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000077	IMP	DNA damage checkpoint
GO:0000738	IEA	DNA catabolic process, exonucleolytic
GO:0003684	TAS	damaged DNA binding
GO:0005515	IPI	protein binding
GO:0005634	IDA:IEA	nucleus
GO:0005654	IDA	nucleoplasm
GO:0005694	IDA	chromosome
GO:0006260	TAS	DNA replication
GO:0006281	IEA	DNA repair
GO:0006974	TAS	cellular response to DNA damage stimulus
GO:0008408	IDA	3'-5' exonuclease activity
GO:0008853	IEA	exodeoxyribonuclease III activity
GO:0021762	IEP	substantia nigra development
GO:0043231	IDA	intracellular membrane-bounded organelle
GO:0051598	IGI	meiotic recombination checkpoint
GO:0071479	IDA	cellular response to ionizing radiation
GO:0090305	IDA	nucleic acid phosphodiester bond hydrolysis

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000168408	Rad1-004	nonsense_mediated_decay	Mus_musculus	0	841
ENSMUST00000022856	Rad1-001	protein_coding	Mus_musculus	0	636
ENSMUST00000170100	Rad1-006	nonsense_mediated_decay	Mus_musculus	0	503
ENSMUST00000170531	Rad1-002	retained_intron	Mus_musculus	0	220
ENSMUST00000169519	Rad1-005	protein_coding	Mus_musculus	0	213
ENSMUST00000100775	Rad1-003	protein_coding	Mus_musculus	0	213

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