C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5'-3' exoribonuclease 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114127 XRN1 9606 - 3:142306607-142448062 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264951 XRN1-001 142306607-142448062 protein_coding
  ENST00000392981 XRN1-004 142311261-142447992 protein_coding
  ENST00000463916 XRN1-003 142417841-142448010 protein_coding
  ENST00000465074 XRN1-008 142435013-142448028 processed_transcript
  ENST00000465507 XRN1-010 142412548-142414340 retained_intron
  ENST00000467077 XRN1-014 142355324-142370588 retained_intron
  ENST00000468894 XRN1-013 142329484-142332890 processed_transcript
  ENST00000470537 XRN1-007 142426564-142448027 retained_intron
  ENST00000472625 XRN1-011 142370485-142375991 retained_intron
  ENST00000472697 XRN1-005 142376249-142425535 retained_intron
  ENST00000477237 XRN1-009 142422635-142429774 protein_coding
  ENST00000486211 XRN1-002 142418419-142448012 nonsense_mediated_decay
  ENST00000489241 XRN1-012 142318647-142335505 nonsense_mediated_decay
  ENST00000498077 XRN1-006 142309392-142412655 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000264951ENST00000392981ENST00000463916ENST00000472697ENST00000498077
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000264951 0.995±0.00 0.695±0.00 0.603±0.00 0.978±0.48 3.771±0.00 1.731±0.00 N/A 5.272±0.00 N/A N/A N/A 0.695±0.00
ENST00000392981 N/A N/A N/A 2.263±0.00 1.948±0.00 0.485±0.00 N/A 2.817±0.00 N/A 1.000±0.00 N/A N/A
ENST00000463916 N/A N/A 1.844±0.00 9.057±0.00 3.192±0.00 1.833±0.00 5.450±0.00 5.478±0.00 10.519±0.00 N/A 6.569±0.00 N/A
ENST00000472697 N/A N/A N/A N/A 2.530±0.00 N/A 3.219±0.00 N/A N/A N/A 3.903±0.00 N/A
ENST00000498077 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.161±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000932 IEA cytoplasmic mRNA processing body
GO:0000956 IMP:IEA nuclear-transcribed mRNA catabolic process
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0004527 IEA exonuclease activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0008409 IEA 5'-3' exonuclease activity
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016075 IMP rRNA catabolic process
GO:0043928 TAS exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0044822 IDA poly(A) RNA binding
GO:0071028 IMP nuclear mRNA surveillance
GO:0071044 IMP histone mRNA catabolic process
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091652 xrn1 5'-3' exoribonuclease 1 protein_coding Danio_rerio
ENSMUSG00000032410 Xrn1 5'-3' exoribonuclease 1 protein_coding Mus_musculus

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