C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 1, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115008 IL1A 9606 - 2:112773915-112784590 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263339 IL1A-001 112773915-112784590 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000263339
Transcript ID Adipose Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000263339 0.029±0.00 0.098±0.00 0.026±0.02 0.004±0.00 0.037±0.00 0.023±0.00 0.668±0.12 2.208±2.51 0.385±0.20 3.632±1.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00018W CIL_00018W_0001 CGP 2:112736607-112784590
CIL_00018X CIL_00018X_0001 CGP 2:112773915-112836903

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001660 IEA fever generation
GO:0002248 IEA connective tissue replacement involved in inflammatory response wound healing
GO:0005125 IMP cytokine activity
GO:0005149 IEA interleukin-1 receptor binding
GO:0005507 IDA copper ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA:IEA extracellular space
GO:0005829 IDA cytosol
GO:0006915 TAS apoptotic process
GO:0006954 TAS:IEA inflammatory response
GO:0006955 IEA immune response
GO:0008283 TAS cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0010575 ISS positive regulation vascular endothelial growth factor production
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0034605 IDA cellular response to heat
GO:0035234 IEA ectopic germ cell programmed cell death
GO:0045086 IMP positive regulation of interleukin-2 biosynthetic process
GO:0045766 ISS positive regulation of angiogenesis
GO:0045840 IMP positive regulation of mitosis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046688 IDA response to copper ion
GO:0050715 IDA positive regulation of cytokine secretion
GO:0051781 IEA positive regulation of cell division
GO:0097192 IEA extrinsic apoptotic signaling pathway in absence of ligand
GO:2001240 TAS negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027399 Il1a interleukin 1 alpha protein_coding Mus_musculus

Loading