C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 1 alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027399 Il1a 10090 - 2:129299610-129309972 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028882 Il1a-001 129299610-129309972 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028882
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028882 0.080±0.03 0.135±0.09 0.168±0.01 0.194±0.05 0.099±0.06 0.055±0.00 0.094±0.01 2.347±1.72 1.605±0.27 0.075±0.02 0.248±0.12 0.939±0.22 0.500±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00018W CIL_00018W_0002 CGP 2:129268210-129309972
CIL_00018X CIL_00018X_0002 CGP 2:129299610-129371139

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001660 IEA fever generation
GO:0002248 IMP connective tissue replacement involved in inflammatory response wound healing
GO:0005125 IEA cytokine activity
GO:0005149 IEA interleukin-1 receptor binding
GO:0005507 ISS copper ion binding
GO:0005515 IEA protein binding
GO:0005615 ISS extracellular space
GO:0005829 ISS cytosol
GO:0006955 IEA immune response
GO:0008285 IEA negative regulation of cell proliferation
GO:0010575 IMP positive regulation vascular endothelial growth factor production
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0034605 ISS cellular response to heat
GO:0035234 IGI ectopic germ cell programmed cell death
GO:0045086 IEA positive regulation of interleukin-2 biosynthetic process
GO:0045766 IMP positive regulation of angiogenesis
GO:0045840 IEA positive regulation of mitosis
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046688 ISS response to copper ion
GO:0050715 IEA positive regulation of cytokine secretion
GO:0051781 IEA positive regulation of cell division
GO:0097192 IMP extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000115008 IL1A interleukin 1, alpha protein_coding Homo_sapiens

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