C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon induced with helicase C domain 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115267 IFIH1 9606 - 2:162267079-162318703 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263642 IFIH1-001 162267079-162318703 protein_coding
  ENST00000421365 IFIH1-002 162310147-162318684 protein_coding
  ENST00000464129 IFIH1-003 162293564-162307170 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263642ENST00000421365ENST00000464129
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263642 2.096±0.00 4.465±0.00 0.750±0.26 3.426±0.51 2.022±0.90 1.528±0.00 4.164±0.91 1.937±0.10 4.012±0.87 0.348±0.26 4.064±1.80 4.098±1.36 2.371±1.46
ENST00000421365 N/A N/A N/A N/A N/A N/A N/A N/A 1.760±0.00 0.123±0.00 N/A N/A N/A
ENST00000464129 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.350±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005KX CIL_0005KX_0001 CGP 2:162170684-162318703
CIL_0005KY CIL_0005KY_0001 CGP 2:162267079-162371595

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003725 TAS double-stranded RNA binding
GO:0003727 IDA single-stranded RNA binding
GO:0004386 IEA helicase activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0008270 IDA zinc ion binding
GO:0009597 TAS detection of virus
GO:0009615 TAS response to virus
GO:0016032 IEA viral process
GO:0016787 IEA hydrolase activity
GO:0016817 IEA hydrolase activity, acting on acid anhydrides
GO:0016925 IDA protein sumoylation
GO:0032480 TAS negative regulation of type I interferon production
GO:0032727 TAS positive regulation of interferon-alpha production
GO:0032728 TAS positive regulation of interferon-beta production
GO:0034344 TAS regulation of type III interferon production
GO:0039528 TAS cytoplasmic pattern recognition receptor signaling pathway in response to virus
GO:0042981 IEA regulation of apoptotic process
GO:0043021 IPI ribonucleoprotein complex binding
GO:0045087 TAS innate immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018553 ifih1 interferon induced with helicase C domain 1 protein_coding Danio_rerio
ENSMUSG00000026896 Ifih1 interferon induced with helicase C domain 1 protein_coding Mus_musculus

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